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SUBSEQUENT EVENTS (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 26, 2022
Oct. 13, 2022
Nov. 13, 2022
Sep. 30, 2022
Sep. 30, 2022
Sep. 30, 2021
Subsequent Event [Line Items]            
Issuance of common stock under the Sales Agreement, net       $ 1,520,000 $ 4,161,000 $ 8,575,000
Subsequent Event            
Subsequent Event [Line Items]            
Issuance of common stock under the Sales Agreement, net     $ 530,442      
Issuance of common stock under the Sales Agreement, net (in shares)     506,990      
Subsequent Event | Pfizer Agreement [Member]            
Subsequent Event [Line Items]            
Proceeds From Sale Of Products     $ 2,300,000      
Subsequent Event | Chiesi Agreements | Alfataliglicerase            
Subsequent Event [Line Items]            
Proceeds from expense reimbursements $ 1,200,000          
Subsequent Event | Brazil Agreement with Fiocruz            
Subsequent Event [Line Items]            
Proceeds From Sale Of Products   $ 1,700,000