SUBSEQUENT EVENTS (Details) - USD ($)			2 Months Ended	3 Months Ended
	May 10, 2022	Apr. 13, 2022	May 16, 2022	Mar. 31, 2021
Subsequent Event [Line Items]
Issuance of common stock under the Sales Agreement				$ 8,575,000
Gross proceeds				$ 8,575,000
Subsequent Event
Subsequent Event [Line Items]
Issuance of common stock under the Sales Agreement			$ 886,000
Issuance of common stock under the Sales Agreement, net (in shares)			746,171
Subsequent Event | Chiesi Agreements
Subsequent Event [Line Items]
Proceeds from expense reimbursements		$ 1,200,000
Subsequent Event | Brazil Agreement with Fiocruz | Alfataliglicerase
Subsequent Event [Line Items]
Proceeds from sales	$ 3,600,000