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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (CAPITAL DEFICIENCY) - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Total
Beginning balance at Dec. 31, 2018 $ 15 $ 269,657 $ (322,553) $ (52,881)
Beginning balance (in shares) at Dec. 31, 2018 14,838,213      
Share-based compensation related to stock options   835   835
Net loss     (18,276) (18,276)
Ending balance at Dec. 31, 2019 $ 15 270,492 (340,829) (70,322)
Ending balance (in shares) at Dec. 31, 2019 14,838,213      
Issuance of common stock and warrants, net of issuance cost $ 18 41,325   41,343
Issuance of common stock and warrants, net of issuance cost (in shares) 17,604,423      
Issuance of common stock under the Sales Agreement, net $ 1 4,866   4,867
Issuance of common stock under the Sales Agreement, net (in shares) 1,428,571      
Share-based compensation related to stock options   2,264   2,264
Share-based compensation related to restricted stock awards $ 1 861   862
Share-based compensation related to restricted stock awards (in shares) 694,073      
Exercise of warrants   472   472
Exercise of warrants (in shares) 200,000      
Net loss     (6,523) (6,523)
Ending balance at Dec. 31, 2020 $ 35 320,280 (347,352) (27,037)
Ending balance (in shares) at Dec. 31, 2020 34,765,280      
Issuance of common stock, net of issuance cost $ 9 37,616   37,625
Issuance of common stock, net of issuance cost (in shares) 8,749,999      
Issuance of common stock under the Sales Agreement, net $ 2 8,573   8,575
Issuance of common stock under the Sales Agreement, net (in shares) 1,867,552      
Share-based compensation related to stock options   1,405   1,405
Share-based compensation related to restricted stock awards   970   970
Exercise of warrants (in shares) 173,816      
Reacquisition of equity component of convertible notes   (12,019)   (12,019)
Equity component of convertible notes, net of transaction costs   12,027   12,027
Net loss     (27,582) (27,582)
Ending balance at Dec. 31, 2021 $ 46 $ 368,852 $ (374,934) $ (6,036)
Ending balance (in shares) at Dec. 31, 2021 45,556,647