CONSOLIDATED STATEMENTS OF INCOME - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
REVENUE:
Total revenue	$ 647,684	$ 576,429	$ 616,619
COST OF SALES	148,461	135,376	127,896
Gross margin	499,223	441,053	488,723
OPERATING EXPENSES:
Research and development	157,187	130,481	117,062
Selling, general and administrative	74,286	67,387	77,886
Amortization of acquired technology and other intangible assets	18,200	15,993	17,459
Patent costs	8,699	9,356	8,329
Royalty and license expense	2,048	647	877
Total operating expenses	260,420	223,864	221,613
OPERATING INCOME	238,803	217,189	267,110
Interest income, net	40,682	28,166	7,811
Other loss, net	(7,357)	(184)	(6,691)
Interest and other loss, net	33,325	27,982	1,120
INCOME BEFORE INCOME TAXES	272,128	245,171	268,230
INCOME TAX EXPENSE	(50,049)	(42,160)	(58,169)
NET INCOME	$ 222,079	$ 203,011	$ 210,061
NET INCOME PER COMMON SHARE:
BASIC	$ 4.66	$ 4.25	$ 4.41
DILUTED	$ 4.65	$ 4.24	$ 4.4
WEIGHTED AVERAGE SHARES USED IN COMPUTING NET INCOME PER COMMON SHARE:
BASIC	47,548,931	47,559,669	47,390,352
DILUTED	47,652,662	47,622,763	47,468,507
CASH DIVIDEND DECLARED PER COMMON SHARE	$ 1.6	$ 1.4	$ 1.2
Material sales
REVENUE:
Total revenue	$ 365,419	$ 322,029	$ 331,081
Royalty and license fees
REVENUE:
Total revenue	266,820	238,389	267,115
Contract research services
REVENUE:
Total revenue	$ 15,445	$ 16,011	$ 18,423