X0202 4 2007-10-10 0 0001005201 DEPOMED INC DEPO 0001252198 HAMILTON JOHN F 1360 O'BRIEN DRIVE MENLO PARK CA 94025 0 1 0 0 VP & CFO Common Stock 2007-10-10 4 A 0 100000 0 A 205644 D Stock Option 3.75 2007-10-10 4 D 0 35000 0 D 2007-12-11 Common Stock 35000 0 D Stock Option 7.625 2007-10-10 4 D 0 25000 0 D 2008-12-09 Common Stock 25000 0 D Stock Option 2.875 2007-10-10 4 D 0 42500 0 D 2009-07-16 Common Stock 42500 0 D Stock Option 3.75 2007-10-10 4 D 0 60000 0 D 2010-06-07 Common Stock 60000 0 D Stock Option 4.3 2007-10-10 4 D 0 40000 0 D 2011-06-05 Common Stock 40000 0 D Stock Option 5.8 2007-10-10 4 D 0 25000 0 D 2011-12-17 Common Stock 25000 0 D Stock Option 1.71 2007-10-10 4 D 0 40000 0 D 2012-12-23 Common Stock 40000 0 D Stock Option 5.08 2007-10-10 4 D 0 25000 0 D 2014-12-20 Common Stock 25000 0 D Stock Option 6.29 2007-10-10 4 D 0 84750 0 D 2016-02-10 Common Stock 84750 0 D Stock Option 4.365 2007-10-10 4 D 0 43750 0 D 2017-05-31 Common Stock 43750 0 D Stock Option 1.98 2007-10-10 4 D 0 50000 0 D 2017-08-24 Common Stock 50000 0 D This option, which provided for vesting with respect to 25% of the underlying shares on December 11, 1998 and with respect to 2.0833% of the underlying shares in each of the thirty-six months thereafter, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting with respect to 25% of the underlying shares on December 9, 1999 and with respect to 2.0833% of the underlying shares in each of the thirty-six months thereafter, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting with respect to 25% of the underlying shares on July 16, 2000 and with respect to 2.0833% of the underlying shares in each of the thirty-six months thereafter, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on July 7, 2000, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on July 5, 2001, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on January 17, 2002, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on January 23, 2003, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on January 20, 2005, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on March 10, 2006, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting in forty-eight monthly installments beginning on June 30, 2007, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. This option, which provided for vesting with respect to 50% of the underlying shares on August 24, 2008 and with respect to 4.1666% of the underlying shares in each of the twelve months thereafter, was cancelled pursuant to a letter agreement between the Company and Mr. Hamilton on October 10, 2007. Issued pursuant to a letter agreement between the Company and Mr. Hamilton dated October 10, 2007. /s/ John F. Hamilton 2007-10-12