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CASH, CASH EQUIVALENTS AND MARKETABLE SECURITIES (Details 3) (Recurring, USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Level 1
    
Fair value hierarchy for financial assets and liabilities    
Assets $ 27,472us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 $ 290,113us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 1 | Corporate debt securities
    
Fair value hierarchy for financial assets and liabilities    
Assets 14,951us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
/ us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis
= us-gaap_CorporateDebtSecuritiesMember		 110,190us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
/ us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis
= us-gaap_CorporateDebtSecuritiesMember
Level 1 | Money market funds
    
Fair value hierarchy for financial assets and liabilities    
Assets 12,521us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_MoneyMarketFundsMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 179,923us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_MoneyMarketFundsMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel1Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 2
    
Fair value hierarchy for financial assets and liabilities    
Assets 16,499us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel2Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 253,837us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel2Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 2 | Commercial Paper
    
Fair value hierarchy for financial assets and liabilities    
Assets 16,499us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_CommercialPaperMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel2Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 253,837us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_CommercialPaperMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel2Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 3
    
Fair value hierarchy for financial assets and liabilities    
Unfavorable contract assumed 1,777depo_UnfavorableContractAssumedFairValueDisclosure
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= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 3,343depo_UnfavorableContractAssumedFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Liabilities 16,496us-gaap_LiabilitiesFairValueDisclosureRecurring
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 17,595us-gaap_LiabilitiesFairValueDisclosureRecurring
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 3 | Zipsor
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 1,760us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
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/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 1,800us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_XanodyneZipsorMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 3 | Lazanda
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 11,617us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_ArchimedeLazandaMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 11,209us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_ArchimedeLazandaMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Level 3 | CAMBIA
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 1,342us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_NautilusCAMBIAMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 1,243us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_NautilusCAMBIAMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value
    
Fair value hierarchy for financial assets and liabilities    
Assets 43,971us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 543,950us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Unfavorable contract assumed 1,777depo_UnfavorableContractAssumedFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 3,343depo_UnfavorableContractAssumedFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Liabilities 16,496us-gaap_LiabilitiesFairValueDisclosureRecurring
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 17,595us-gaap_LiabilitiesFairValueDisclosureRecurring
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value | Zipsor
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 1,760us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_XanodyneZipsorMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 1,800us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_XanodyneZipsorMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value | Lazanda
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 11,617us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_ArchimedeLazandaMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 11,209us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_ArchimedeLazandaMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value | CAMBIA
    
Fair value hierarchy for financial assets and liabilities    
Liabilities, contingent consideration 1,342us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_NautilusCAMBIAMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 1,243us-gaap_BusinessCombinationContingentConsiderationLiability
/ us-gaap_BusinessAcquisitionAxis
= depo_NautilusCAMBIAMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value | Corporate debt securities
    
Fair value hierarchy for financial assets and liabilities    
Assets 14,951us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
/ us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis
= us-gaap_CorporateDebtSecuritiesMember		 110,190us-gaap_AssetsFairValueDisclosure
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
/ us-gaap_MajorTypesOfDebtAndEquitySecuritiesAxis
= us-gaap_CorporateDebtSecuritiesMember
Fair Value | Money market funds
    
Fair value hierarchy for financial assets and liabilities    
Assets 12,521us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_MoneyMarketFundsMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 179,923us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_MoneyMarketFundsMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember
Fair Value | Commercial Paper
    
Fair value hierarchy for financial assets and liabilities    
Assets $ 16,499us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_CommercialPaperMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember		 $ 253,837us-gaap_AssetsFairValueDisclosure
/ us-gaap_CashAndCashEquivalentsAxis
= us-gaap_CommercialPaperMember
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_EstimateOfFairValueFairValueDisclosureMember
/ us-gaap_FairValueByMeasurementFrequencyAxis
= us-gaap_FairValueMeasurementsRecurringMember