CONDENSED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Sep. 30, 2013	Dec. 31, 2012
Current assets:
Cash and cash equivalents	$ 64,282	$ 29,076
Marketable securities	16,294	37,737
Accounts receivable	8,312	3,614
Receivables from collaborative partners	7,769	10,078
Inventories	7,822	9,587
Prepaid and other current assets	6,142	5,175
Total current assets	110,621	95,267
Marketable securities, long-term	4,786	11,079
Property and equipment, net	8,382	8,237
Intangible assets, net	32,626	25,078
Other assets	329	1,992
TOTAL ASSETS	156,744	141,653
Current liabilities:
Accounts payable and accrued liabilities	30,288	32,578
Deferred license revenue	3,182	3,273
Other current liabilities	649	830
Total current liabilities	34,119	36,681
Deferred license revenue, non-current portion	13,235	15,516
Contingent consideration liability	9,787	1,342
Other long-term liabilities	7,390	4,178
Commitments
Shareholders' equity:
Preferred stock, no par value, 5,000,000 shares authorized; Series A convertible preferred stock, 25,000 shares designated, 18,158 shares issued and surrendered, and zero shares outstanding at September 30, 2013 and December 31, 2012
Common stock, no par value, 100,000,000 shares authorized; 56,925,105 and 56,383,713 shares issued and outstanding at September 30, 2013 and December 31, 2012, respectively	218,070	211,266
Accumulated deficit	(125,849)	(127,361)
Accumulated other comprehensive gain, net of tax	(8)	31
Total shareholders' equity	92,213	83,936
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY	$ 156,744	$ 141,653