Condensed Balance Sheets (USD $) In Thousands, unless otherwise specified	Mar. 31, 2013	Dec. 31, 2012
ASSETS
Cash and cash equivalents	$ 21,930	$ 29,076
Marketable securities	44,423	37,737
Accounts receivable	5,292	3,614
Receivables from collaborative partners	10,015	10,078
Inventories	8,743	9,587
Prepaid and other current assets	5,608	5,175
Total current assets	96,011	95,267
Marketable securities, long-term	6,536	11,079
Property and equipment, net	8,090	8,237
Intangible assets, net	24,267	25,078
Other assets	324	1,992
TOTAL ASSETS	135,228	141,653
LIABILITIES AND SHAREHOLDERS' EQUITY
Accounts payable and accrued liabilities	27,926	32,578
Deferred license revenue	3,041	3,273
Other current liabilities	1,098	830
Total current liabilities	32,065	36,681
Deferred license revenue, non-current portion	14,756	15,516
Other long-term liabilities	8,151	5,520
Commitments
Shareholders' equity:
Common stock, no par value	213,085	211,266
Accumulated deficit	(132,841)	(127,361)
Accumulated other comprehensive gain (loss)	12	31
Total shareholders' equity	80,256	83,936
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY	$ 135,228	$ 141,653