CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Operating Activities
Net (loss) income	$ (217,201)	$ 36,908	$ (102,496)
Adjustments for non-cash items:
Depreciation and amortization	102,946	106,426	105,502
Accretion of debt discount and debt issuance costs	23,764	21,877	19,415
Provisions for inventory and other assets	5,304	598	2,673
Loss on impairment of intangible asset	189,790	0	0
Loss (gain) on disposal of equipment	10,076	669	(271)
Stock-based compensation	10,596	12,585	13,016
Intraperiod tax allocations	(5,767)	0	0
(Gain) loss on debt extinguishment and prepayment	(26,385)	0	5,938
Recurring fair value measurement of assets and liabilities	(1,715)	(391)	(8,024)
Gain on divestiture of Lazanda	0	0	(17,064)
Acquired in-process research and development	0	0	24,900
Other	(327)	1,023	240
Changes in assets and liabilities:
Accounts receivable	(5,533)	35,271	30,107
Inventories	(316)	9,048	(1,873)
Prepaid and other assets	40,769	(56,136)	(5,114)
Accounts payable and other accrued liabilities	(15,146)	(33,610)	(6,436)
Accrued rebates, returns and discounts	(16,816)	(60,069)	4,292
Interest payable	(3,270)	(1,576)	(2,705)
Income taxes payable	(294)	(126)	67
Net cash provided by operating activities	90,475	72,497	62,167
Investing Activities
Purchases of property and equipment	(1,481)	(5,507)	(666)
Investment in convertible instrument	0	(3,000)	0
Proceeds from disposal of property and equipment	0	145	280
Purchases of marketable securities	(12,065)	0	(8,277)
Proceeds from sale of other assets	0	80	66,557
Maturities of marketable securities	4,209	0	0
Sales of marketable securities	7,856	1,200	0
Net cash (used in) provided by investing activities	(1,481)	(7,082)	57,894
Financing Activities
Payment of contingent consideration liability	0	(184)	(1,673)
Repayment of Senior Notes	(120,000)	(82,500)	(110,000)
Fees for early repayment and modifications of Senior Notes and payments in conjunction with debt extinguishment	(30,000)	0	(7,400)
Fees for modification of Senior Notes	(3,249)	0	0
Convertible notes issuance costs	(4,268)	0	0
Proceeds from issuance of common stock	251	2,020	8,940
Shares withheld for payment of employee's withholding tax liability	(570)	(686)	(753)
Net cash used in financing activities	(157,836)	(81,350)	(110,886)
Net (decrease) increase in cash and cash equivalents	(68,842)	(15,935)	9,175
Cash and cash equivalents at beginning of year	110,949	126,884	117,709
Cash and cash equivalents at end of period	42,107	110,949	126,884
Supplemental Disclosure of Cash Flow Information
Net cash paid (received) for income taxes	4,401	6,472	121
Cash paid for interest	37,788	48,440	55,542
Non-cash consideration for in-process research and development	0	0	19,900
Accrued research and development	0	0	5,000
Capital expenditures incurred but not yet paid	$ 500	$ 212	$ 0