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    <isConfidential>false</isConfidential>
    <filerInfo>

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          <cik>0000100334</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


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      <regName>American Century Mutual Funds, Inc.</regName>
      <regFileNumber>811-00816</regFileNumber>
      <regCik>0000100334</regCik>
      <regLei>549300DMFK0SMVLOE939</regLei>
      <regStreet1>4500 Main St</regStreet1>
      <regCity>Kansas City</regCity>
      <regStateConditional regCountry="US" regState="US-MO"/>
      <regZipOrPostalCode>64111</regZipOrPostalCode>
      <regPhone>816-531-5575</regPhone>
      <seriesName> Select Fund</seriesName>
      <seriesId>S000006194</seriesId>
      <seriesLei>YBV2RHBLCMLT5C6UGK81</seriesLei>
      <repPdEnd>2025-10-31</repPdEnd>
      <repPdDate>2025-10-31</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
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      <totLiabs>5058605.640000000000</totLiabs>
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      <assetsInvested>0.000000000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000000000</amtPayOneYrBanksBorr>
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        <borrower aggrVal="75767.510000000000" lei="549300BLWPABP1VNME36" name="SCOTIA CAPITAL (USA) INC."/>
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      <isNonCashCollateral>N</isNonCashCollateral>
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        <name>UL Solutions Inc</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>State Street Navigator Securities Lending Trust - State Street Navigator Securities Lending Government Money Market Portfolio</name>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>KLA Corp</name>
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        <name>Eli Lilly &amp; Co</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>Lincoln Electric Holdings Inc</name>
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        <name>Lowe's Cos Inc</name>
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        <name>Veralto Corp</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>MSCI Inc</name>
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        <isRestrictedSec>N</isRestrictedSec>

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        <isRestrictedSec>N</isRestrictedSec>

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        <isRestrictedSec>N</isRestrictedSec>

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        <name>Mastercard Inc</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>Mettler-Toledo International Inc</name>
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        <isRestrictedSec>N</isRestrictedSec>

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        <name>Microsoft Corp</name>
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        <title>Microsoft Corp</title>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
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      </invstOrSec>
      <invstOrSec>
        <name>Netflix Inc</name>
        <lei>549300Y7VHGU0I7CE873</lei>
        <title>Netflix Inc</title>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
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      </invstOrSec>
      <invstOrSec>
        <name>NVIDIA Corp</name>
        <lei>549300S4KLFTLO7GSQ80</lei>
        <title>NVIDIA Corp</title>
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        <balance>5151000.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1043025990.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>Oracle Corp</name>
        <lei>1Z4GXXU7ZHVWFCD8TV52</lei>
        <title>Oracle Corp</title>
        <cusip>68389X105</cusip>
        <identifiers>
          <isin value="US68389X1054"/>
          <ticker value="ORCL"/>
          <other otherDesc="SEDOL" value="2661568"/>
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        <balance>585100.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>153653111.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>Palantir Technologies Inc</name>
        <lei>549300UVN46B3BBDHO85</lei>
        <title>Palantir Technologies Inc</title>
        <cusip>69608A108</cusip>
        <identifiers>
          <isin value="US69608A1088"/>
          <ticker value="PLTR"/>
          <other otherDesc="SEDOL" value="BN78DQ4"/>
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        <balance>196000.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>39292120.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Pinterest Inc</name>
        <lei>N/A</lei>
        <title>Pinterest Inc</title>
        <cusip>72352L106</cusip>
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          <isin value="US72352L1061"/>
          <ticker value="PINS"/>
          <other otherDesc="SEDOL" value="BJ2Z0H2"/>
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        <balance>1272700.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>42126370.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Progressive Corp/The</name>
        <lei>N/A</lei>
        <title>Progressive Corp/The</title>
        <cusip>743315103</cusip>
        <identifiers>
          <isin value="US7433151039"/>
          <ticker value="PGR"/>
          <other otherDesc="SEDOL" value="2705024"/>
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        <balance>281100.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>57906600.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Regeneron Pharmaceuticals Inc</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>Regeneron Pharmaceuticals Inc</title>
        <cusip>75886F107</cusip>
        <identifiers>
          <isin value="US75886F1075"/>
          <ticker value="REGN"/>
          <other otherDesc="SEDOL" value="2730190"/>
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        <balance>68500.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>44648300.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Roper Technologies Inc</name>
        <lei>54930003T4SXCIWVXY35</lei>
        <title>Roper Technologies Inc</title>
        <cusip>776696106</cusip>
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          <isin value="US7766961061"/>
          <ticker value="ROP"/>
          <other otherDesc="SEDOL" value="2749602"/>
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        <balance>86900.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>38770435.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>salesforce.com Inc</name>
        <lei>RCGZFPDMRW58VJ54VR07</lei>
        <title>Salesforce Inc</title>
        <cusip>79466L302</cusip>
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          <isin value="US79466L3024"/>
          <ticker value="CRM"/>
          <other otherDesc="SEDOL" value="2310525"/>
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        <balance>156000.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>40623960.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Stryker Corp</name>
        <lei>5493002F0SC4JTBU5137</lei>
        <title>Stryker Corp</title>
        <cusip>863667101</cusip>
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          <isin value="US8636671013"/>
          <ticker value="SYK"/>
          <other otherDesc="SEDOL" value="2853688"/>
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        <balance>103000.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>36692720.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>TJX Cos Inc/The</name>
        <lei>V167QI9I69W364E2DY52</lei>
        <title>TJX Cos Inc/The</title>
        <cusip>872540109</cusip>
        <identifiers>
          <isin value="US8725401090"/>
          <ticker value="TJX"/>
          <other otherDesc="SEDOL" value="2989301"/>
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        <balance>498100.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>69803734.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Taiwan Semiconductor Manufacturing Co Ltd</name>
        <lei>549300KB6NK5SBD14S87</lei>
        <title>Taiwan Semiconductor Manufacturing Co Ltd</title>
        <cusip>874039100</cusip>
        <identifiers>
          <isin value="US8740391003"/>
          <ticker value="TSM"/>
          <other otherDesc="SEDOL" value="2113382"/>
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        <balance>415200.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>124738536.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>TW</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Tesla Inc</name>
        <lei>54930043XZGB27CTOV49</lei>
        <title>Tesla Inc</title>
        <cusip>88160R101</cusip>
        <identifiers>
          <isin value="US88160R1014"/>
          <ticker value="TSLA"/>
          <other otherDesc="SEDOL" value="B616C79"/>
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        <balance>616500.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>281469240.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Verisk Analytics Inc</name>
        <lei>549300I1YSWNIRKBWP67</lei>
        <title>Verisk Analytics Inc</title>
        <cusip>92345Y106</cusip>
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          <isin value="US92345Y1064"/>
          <ticker value="VRSK"/>
          <other otherDesc="SEDOL" value="B4P9W92"/>
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        <balance>43200.0000000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Zscaler Inc</name>
        <lei>529900MZ0RTK1BWRNF46</lei>
        <title>Zscaler Inc</title>
        <cusip>98980G102</cusip>
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          <ticker value="ZS"/>
          <other otherDesc="SEDOL" value="BZ00V34"/>
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        <balance>261100.0000000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Adobe Inc</name>
        <lei>FU4LY2G4933NH2E1CP29</lei>
        <title>Adobe Inc</title>
        <cusip>00724F101</cusip>
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          <ticker value="ADBE"/>
          <other otherDesc="SEDOL" value="2008154"/>
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        <balance>67700.0000000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Airbnb Inc</name>
        <lei>549300HMUDNO0RY56D37</lei>
        <title>Airbnb Inc</title>
        <cusip>009066101</cusip>
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          <ticker value="ABNB"/>
          <other otherDesc="SEDOL" value="BMGYYH4"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Alphabet Inc</name>
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        <title>Alphabet Inc-CL C</title>
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          <ticker value="GOOG"/>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Alphabet Inc</name>
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        <title>Alphabet Inc</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Amazon.com Inc</name>
        <lei>ZXTILKJKG63JELOEG630</lei>
        <title>Amazon.com Inc</title>
        <cusip>023135106</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>American Express Co</name>
        <lei>R4PP93JZOLY261QX3811</lei>
        <title>American Express Co</title>
        <cusip>025816109</cusip>
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          <ticker value="AXP"/>
          <other otherDesc="SEDOL" value="2026082"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Analog Devices Inc</name>
        <lei>GYVOE5EZ4GDAVTU4CQ61</lei>
        <title>Analog Devices Inc</title>
        <cusip>032654105</cusip>
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          <ticker value="ADI"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Apple Inc</name>
        <lei>HWUPKR0MPOU8FGXBT394</lei>
        <title>Apple Inc</title>
        <cusip>037833100</cusip>
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          <ticker value="AAPL"/>
          <other otherDesc="SEDOL" value="2046251"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>AppLovin Corp</name>
        <lei>549300LLVXMUAOL3SQ07</lei>
        <title>AppLovin Corp</title>
        <cusip>03831W108</cusip>
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          <isin value="US03831W1080"/>
          <ticker value="APP"/>
          <other otherDesc="SEDOL" value="BMV3LG4"/>
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        <balance>173600.0000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>110640488.0000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Arista Networks Inc</name>
        <lei>635400H1WKBLOQERUU95</lei>
        <title>Arista Networks Inc</title>
        <cusip>040413205</cusip>
        <identifiers>
          <isin value="US0404132054"/>
          <ticker value="ANET"/>
          <other otherDesc="SEDOL" value="BL9XPM3"/>
        </identifiers>
        <balance>305900.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>48237371.0000000000</valUSD>
        <pctVal>0.7233974572</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Boston Scientific Corp</name>
        <lei>Y6ZDD9FP4P8JSSJMW954</lei>
        <title>Boston Scientific Corp</title>
        <cusip>101137107</cusip>
        <identifiers>
          <isin value="US1011371077"/>
          <ticker value="BSX"/>
          <other otherDesc="SEDOL" value="2113434"/>
        </identifiers>
        <balance>806100.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>81190392.0000000000</valUSD>
        <pctVal>1.2175813462</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Broadridge Financial Solutions Inc</name>
        <lei>N/A</lei>
        <title>Broadridge Financial Solutions Inc</title>
        <cusip>11133T103</cusip>
        <identifiers>
          <isin value="US11133T1034"/>
          <ticker value="BR"/>
          <other otherDesc="SEDOL" value="B1VP7R6"/>
        </identifiers>
        <balance>153500.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>33831400.0000000000</valUSD>
        <pctVal>0.5073566039</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Broadcom Inc</name>
        <lei>549300WV6GIDOZJTV909</lei>
        <title>Broadcom Inc</title>
        <cusip>11135F101</cusip>
        <identifiers>
          <isin value="US11135F1012"/>
          <ticker value="AVGO"/>
          <other otherDesc="SEDOL" value="BDZ78H9"/>
        </identifiers>
        <balance>567300.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>209691099.0000000000</valUSD>
        <pctVal>3.1446574444</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Burlington Stores Inc</name>
        <lei>5299003Z37DVGKKC1W09</lei>
        <title>Burlington Stores Inc</title>
        <cusip>122017106</cusip>
        <identifiers>
          <isin value="US1220171060"/>
          <ticker value="BURL"/>
          <other otherDesc="SEDOL" value="BF311Y5"/>
        </identifiers>
        <balance>124600.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>34089314.0000000000</valUSD>
        <pctVal>0.5112244418</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cheniere Energy Inc</name>
        <lei>MIHC87W9WTYSYZWV1J40</lei>
        <title>Cheniere Energy Inc</title>
        <cusip>16411R208</cusip>
        <identifiers>
          <isin value="US16411R2085"/>
          <ticker value="LNG"/>
          <other otherDesc="SEDOL" value="2654364"/>
        </identifiers>
        <balance>198400.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>42060800.0000000000</valUSD>
        <pctVal>0.6307697774</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Costco Wholesale Corp</name>
        <lei>29DX7H14B9S6O3FD6V18</lei>
        <title>Costco Wholesale Corp</title>
        <cusip>22160K105</cusip>
        <identifiers>
          <isin value="US22160K1051"/>
          <ticker value="COST"/>
          <other otherDesc="SEDOL" value="2701271"/>
        </identifiers>
        <balance>110500.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>100715225.0000000000</valUSD>
        <pctVal>1.5103878208</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Crowdstrike Holdings Inc</name>
        <lei>549300YBY08K9KM4HX32</lei>
        <title>Crowdstrike Holdings Inc</title>
        <cusip>22788C105</cusip>
        <identifiers>
          <isin value="US22788C1053"/>
          <ticker value="CRWD"/>
          <other otherDesc="SEDOL" value="BJJP138"/>
        </identifiers>
        <balance>145600.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>79062256.0000000000</valUSD>
        <pctVal>1.1856665022</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Danaher Corp</name>
        <lei>S4BKK9OTCEWQ3YHPFM11</lei>
        <title>Danaher Corp</title>
        <cusip>235851102</cusip>
        <identifiers>
          <isin value="US2358511028"/>
          <ticker value="DHR"/>
          <other otherDesc="SEDOL" value="2250870"/>
        </identifiers>
        <balance>174700.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>37626886.0000000000</valUSD>
        <pctVal>0.5642760600</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Walt Disney Co/The</name>
        <lei>7260JQNI6SCF9FIV2392</lei>
        <title>Walt Disney Co/The</title>
        <cusip>254687106</cusip>
        <identifiers>
          <isin value="US2546871060"/>
          <ticker value="DIS"/>
          <other otherDesc="SEDOL" value="2270726"/>
        </identifiers>
        <balance>340000.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38290800.0000000000</valUSD>
        <pctVal>0.5742325251</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Meta Platforms Inc</name>
        <lei>BQ4BKCS1HXDV9HN80Z93</lei>
        <title>Meta Platforms Inc</title>
        <cusip>30303M102</cusip>
        <identifiers>
          <isin value="US30303M1027"/>
          <ticker value="META"/>
          <other otherDesc="SEDOL" value="B7TL820"/>
        </identifiers>
        <balance>498500.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>323202475.0000000000</valUSD>
        <pctVal>4.8469442618</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GE Vernova Inc</name>
        <lei>254900DP080RU6OK2553</lei>
        <title>GE Vernova Inc</title>
        <cusip>36828A101</cusip>
        <identifiers>
          <isin value="US36828A1016"/>
          <ticker value="GEV"/>
          <other otherDesc="SEDOL" value="BP6H4Y1"/>
        </identifiers>
        <balance>76600.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>44821724.0000000000</valUSD>
        <pctVal>0.6721743017</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Gilead Sciences Inc</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>Gilead Sciences Inc</title>
        <cusip>375558103</cusip>
        <identifiers>
          <isin value="US3755581036"/>
          <ticker value="GILD"/>
          <other otherDesc="SEDOL" value="2369174"/>
        </identifiers>
        <balance>570800.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>68376132.0000000000</valUSD>
        <pctVal>1.0254107758</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Graco Inc</name>
        <lei>4T5VJ4S81BRT6Q7GGT78</lei>
        <title>Graco Inc</title>
        <cusip>384109104</cusip>
        <identifiers>
          <isin value="US3841091040"/>
          <ticker value="GGG"/>
          <other otherDesc="SEDOL" value="2380443"/>
        </identifiers>
        <balance>293100.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23966787.0000000000</valUSD>
        <pctVal>0.3594207647</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Ionis Pharmaceuticals Inc</name>
        <lei>549300SI4ZGLG0BLUZ92</lei>
        <title>Ionis Pharmaceuticals Inc</title>
        <cusip>462222100</cusip>
        <identifiers>
          <isin value="US4622221004"/>
          <ticker value="IONS"/>
          <other otherDesc="SEDOL" value="BDJ0LS6"/>
        </identifiers>
        <balance>917600.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>68177680.0000000000</valUSD>
        <pctVal>1.0224346669</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>State Street Institutional US Government Money Market Fund</name>
        <lei>549300BZ5TGIFZUZDZ37</lei>
        <title>State Street Institutional US Government Money Market Fund</title>
        <cusip>857492706</cusip>
        <identifiers>
          <isin value="US8574927062"/>
          <ticker value="GVMXX"/>
          <other otherDesc="SEDOL" value="B284MN4"/>
        </identifiers>
        <balance>39149.8500000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>39149.8500000000</valUSD>
        <pctVal>0.0005871154</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>State Street Bank &amp; Trust Co</name>
        <lei>571474TGEMMWANRLN572</lei>
        <title>Fixed Income Clearing Corp 4.15 11/03/2025</title>
        <cusip>RPEV0P0O6</cusip>
        <identifiers>
          <ticker value="STBK"/>
        </identifiers>
        <balance>24529000.0000000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>24529000.0000000000</valUSD>
        <pctVal>0.3678520587</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2025-11-03</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>4.15</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <clearedCentCparty centralCounterparty="Fixed Income Clearing Corp." isCleared="Y"/>
          <isTriParty>N</isTriParty>
          <repurchaseRt>4.15</repurchaseRt>
          <maturityDt>2025-11-03</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>25108800</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>25019597.47</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2025-12-29</ncom:dateSigned>
      <ncom:nameOfApplicant>American Century Mutual Funds, Inc.</ncom:nameOfApplicant>
      <ncom:signature>Amy R. Bitter</ncom:signature>
      <ncom:signerName>Amy R. Bitter</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
