As Filed with the U.S. Securities and Exchange Commission on March 20, 2020

1933 Act File No. 002-14213

1940 Act File No. 811-00816

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549
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FORM N-1A
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REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933	☒
Pre-Effective Amendment No.	☐
Post-Effective Amendment No. 162	☒
and/or
REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940	☒
Amendment No. 161	☒
(Check appropriate box or boxes.)
__________________
American Century Mutual Funds, Inc. (Exact Name of Registrant as Specified in Charter)
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4500 MAIN STREET, KANSAS CITY, MISSOURI 64111 (Address of Principal Executive Offices) (Zip Code)
REGISTRANT’S TELEPHONE NUMBER, INCLUDING AREA CODE: (816) 531-5575
CHARLES A. ETHERINGTON 4500 MAIN STREET, KANSAS CITY, MISSOURI 64111 (Name and Address of Agent for Service)
It is proposed that this filing will become effective (check appropriate box)

x	immediately upon filing pursuant to paragraph (b)
☐	on (date) pursuant to paragraph (b)
☐	60 days after filing pursuant to paragraph (a)(1)
☐	on (date) pursuant to paragraph (a)(1)
☐	75 days after filing pursuant to paragraph (a)(2)
☐	on (date) pursuant to paragraph (a)(2) of rule 485.
If appropriate, check the following box:
☐	this post-effective amendment designates a new effective date for a previously filed post-effective amendment.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the Investment Company Act of 1940, the Registrant certifies that it meets all of the requirements for effectiveness of this Registration Statement amendment pursuant to Rule 485(b) promulgated under the Securities Act of 1933, as amended, and has duly caused this amendment to be signed on its behalf by the undersigned, duly authorized, in the City of Kansas City, State of Missouri on the 20^th day of March, 2020.

American Century Mutual Funds, Inc.

(Registrant)

By:

*

___________________________________

Patrick Bannigan

President

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement amendment has been signed by the following persons in the capacities and on the dates indicated.

SIGNATURE	TITLE	DATE
*	President	March 20, 2020
Patrick Bannigan
*	Chief Financial Officer and Treasurer	March 20, 2020
R. Wes Campbell
*	Director	March 20, 2020
Thomas W. Bunn
*	Director	March 20, 2020
Chris H. Cheesman
*	Director	March 20, 2020
Barry Fink
*	Director	March 20, 2020
Rajesh K. Gupta
*	Director	March 20, 2020
Lynn Jenkins
*	Director	March 20, 2020
Jan M. Lewis
*	Director	March 20, 2020
Jonathan S. Thomas
*	Director	March 20, 2020
John R. Whitten
*	Director and Chairman of the Board	March 20, 2020
Stephen E. Yates

*By:        /s/ Evan C. Johnson

____________________________________

Evan C. Johnson

Attorney in Fact

(pursuant to Power of Attorney

effective September 11, 2019)

Pursuant to Power of Attorney, effective September 11, 2019 (filed electronically as Exhibit q1 to Post-Effective Amendment No. 81 to the Registration Statement of American Century World Mutual Funds, Inc. on September 17, 2019, File No. 33-39242, and incorporated herein by reference).

Secretary’s Certificate, effective September 11, 2019 (filed electronically as Exhibit q2 to Post-Effective Amendment No. 81 to the Registration Statement of American Century World Mutual Funds, Inc. on September 17, 2019, File No. 33-39242, and incorporated herein by reference).

EXHIBIT INDEX

EXHIBIT NUMBER	DESCRIPTION OF DOCUMENT
Exhibit - 101.CAL	XBRL Taxonomy Extension Calculation Linkbase Document
Exhibit - 101.INS	XBRL Instance Document
Exhibit - 101.SCH	XBRL Taxonomy Extension Schema Document
Exhibit - 101.PRE	XBRL Taxonomy Extension Presentation Linkbase Document
Exhibit - 101.DEF	XBRL Taxonomy Extension Definition Linkbase Document
Exhibit - 101.LAB	XBRL Taxonomy Extension Label Linkbase Document