X0202 4 2006-10-20 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001285101 SHANNON COLIN 216 GATEFIELD DRIVE WILMINGTON NC 28412 0 1 0 0 EVP, Global Clinical Ops Common Stock 2006-10-20 4 M 0 9000 14.22 A 9000 D Common Stock 2006-10-20 4 M 0 9667 15.43 A 18667 D Common Stock 2006-10-20 4 M 0 20000 17.15 A 38667 D Common Stock 2006-10-20 4 M 0 32500 21.19 A 71167 D Common Stock 2006-10-20 4 S 0 20000 35.49 D 51167 D Common Stock 2006-10-20 4 S 0 11167 35.45 D 40000 D Common Stock 2006-10-20 4 S 0 15000 35.41 D 25000 D Common Stock 2006-10-20 4 S 0 3000 35.35 D 22000 D Common Stock 2006-10-20 4 S 0 22000 35.30 D 0 D Stock Options (to buy) 14.22 2006-10-20 4 M 0 9000 0 D 2006-02-13 2013-02-12 Common Stock 9000 0 D Stock Options (to buy) 15.43 2006-10-20 4 M 0 9667 0 D 2006-03-04 2014-03-03 Common Stock 9667 9667 D Stock Options (to buy) 17.15 2006-10-20 4 M 0 20000 0 D 2006-07-16 2014-07-15 Common Stock 20000 20000 D Stock Options (to buy) 21.19 2006-10-20 4 M 0 32500 0 D 2005-11-16 2014-11-15 Common Stock 32500 97500 D Stock Options (to buy) 34.62 2007-02-22 2016-02-21 Common Stock 40000 40000 D 13,333 options are vested and exercisable on 2/22/07; 13,333 options are vested and exercisable on 2/22/08; and 13,334 options are vested and exercisable on 2/22/09. Lisa C. Noecker attorney-in-fact for Colin Shannon 2006-10-23