X0202 4 2006-02-23 0001003124 PHARMACEUTICAL PRODUCT DEVELOPMENT INC PPDI 0001181153 COVINGTON PAUL S 3116 BRAEMAR DRIVE WILMINGTON NC 28409 0 1 0 0 Executive Vice President Common Stock 2006-02-23 4 M 0 6667 29.89 A 11620 D Common Stock 2006-02-23 4 M 0 6667 30.60 A 18287 D Common Stock 2006-02-23 4 M 0 12500 42.38 A 30787 D Common Stock 2006-02-23 4 S 0 6667 69.30 D 24120 D Common Stock 2006-02-23 4 S 0 6667 69.35 D 17453 D Common Stock 2006-02-23 4 S 0 1000 69.50 D 16453 D Common Stock 2006-02-23 4 S 0 11500 69.30 D 4953 D Stock Options (to buy) 29.89 2006-02-23 4 M 0 6667 0 D 2005-12-03 2012-12-02 Common Stock 6667 83334 D Stock Options (to buy) 30.60 2006-02-23 4 M 0 6667 0 D 2005-12-03 2013-12-02 Common Stock 6667 76667 D Stock Options (to buy) 42.38 2006-02-23 4 M 0 12500 0 D 2005-11-16 2014-11-15 Common Stock 12500 64167 D Lisa C. Noecker attorney-in-fact for Paul S. Covington 2006-02-24