SEC FORM 4

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Protopapas Anna

(Last)

(First)

(Middle)

MILLENNIUM PHARMACEUTICALS, INC.

40 LANDSDOWNE STREET

(Street)

CAMBRIDGE

02139

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
MILLENNIUM PHARMACEUTICALS INC [ MLNM ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Senior Vice President

3. Date of Earliest Transaction (Month/Day/Year)
03/09/2007

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common stock	03/09/2007		M		1,222	A	$4.9063	130,581	D
Common stock	03/09/2007		M		2,081	A	$4.7188	132,662	D
Common stock	03/09/2007		M		76	A	$1.4017	132,738	D
Common stock	03/09/2007		M		184	A	$1.4017	132,922	D
Common stock	03/09/2007		M		80	A	$0.065	133,002	D
Common stock	03/09/2007		M		190	A	$1.125	133,192	D
Common stock	03/09/2007		S		100	D	$10.6001	133,092	D
Common stock	03/09/2007		S		1,200	D	$10.59	131,892	D
Common stock	03/09/2007		S		1,400	D	$10.58	130,492	D
Common stock	03/09/2007		S		1,133	D	$10.57	129,359	D
Common stock	03/12/2007		S⁽¹⁾		1,970	D	$10.64	127,389	D
Common stock								4,979	I	by 401(k) plan account

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Employee stock option (right to buy)	$4.9063	03/09/2007		M			1,222	⁽²⁾	10/09/2007	Common stock	1,222	$0	0	D
Employee stock option (right to buy)	$4.7188	03/09/2007		M			2,081	⁽³⁾	04/22/2008	Common stock	2,081	$0	0	D
Employee stock option (right to buy)	$1.4017	03/09/2007		M			76	12/31/2005	01/26/2009	Common stock	76	$0	0	D
Employee stock option (right to buy)	$1.4017	03/09/2007		M			184	⁽⁴⁾	04/12/2009	Common stock	184	$0	0	D
Employee stock option (right to buy)	$0.065	03/09/2007		M			80	12/31/2005	01/21/2009	Common stock	80	$0	0	D
Employee stock option (right to buy)	$1.125	03/09/2007		M			190	⁽⁵⁾	02/25/2009	Common stock	190	$0	0	D

Explanation of Responses:

1. Pursuant to a trading plan previously established by the reporting person under Rule 10b5-1 of the Secutities Exchange Act of 1934, as amended, these shares were sold to cover withholding taxes on shares of restricted stock that vested on 03/06/2007.

2. Became exercisable for 1/4th of the total number of shares granted on 10/09/1998 and for 1/48th of the total number of shares granted monthly thereafter beginning 11/09/1998.

3. Became exercisable for 1/48th of the total number of shares granted on 04/22/1998 and for 1/48th of the total number of shares granted monthly beginning on 05/01/1998.

4. Became exercisable for 1/48th of the total number of shares granted on 04/12/1999 and for 1/48th of the total number of shares granted monthly thereafter beginning 05/01/1999.

5. Became exercisable for 1/48th of the total number of shares granted monthly beginning 04/01/1999.

Remarks:

	Joel S. Goldberg, Attorney-In-Fact	03/13/2007
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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