QUARTERLY FINANCIAL INFORMATION

12 Months Ended

Dec. 31, 2018

Disclosure Text Block [Abstract]

QUARTERLY FINANCIAL INFORMATION

(in thousands)	3 Months Ended
	March 31, 2018			June 30, 2018			September 30, 2018			December 31, 2018
License revenue	$	38		$	38		$	38		$	38
Total costs and expenses		40,615			44,383			34,366			54,188
Net loss	$	(41,529	)	$	(44,142	)	$	(33,951	)	$	(53,861	)
Basic and diluted net loss per common share	$	(0.59	)	$	(0.59	)	$	(0.43	)	$	(0.68	)

(in thousands)	3 Months Ended
	March 31, 2017			June 30, 2017			September 30, 2017			December 31, 2017
License revenue	$	38		$	38		$	38		$	38
Total costs and expenses		27,704			28,463			31,623			31,073
Net loss	$	(27,727	)	$	(28,353	)	$	(31,536	)	$	(30,860	)
Basic and diluted net loss per common share	$	(0.52	)	$	(0.45	)	$	(0.48	)	$	(0.46	)