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Condensed Consolidated Statements of Operations - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Income Statement [Abstract]        
License revenue $ 38,096 $ 38,096 $ 114,286 $ 114,286
Research and development:        
Noncash compensation 1,814,288 919,648 5,386,709 1,873,730
Other research and development 25,334,762 20,878,108 71,150,033 45,075,097
Total research and development 27,149,050 21,797,756 76,536,742 46,948,827
General and administrative:        
Noncash compensation 3,075,835 1,914,390 6,988,597 4,307,670
Other general and administrative 1,398,438 1,251,421 4,265,967 3,798,859
Total general and administrative 4,474,273 3,165,811 11,254,564 8,106,529
Total costs and expenses 31,623,323 24,963,567 87,791,306 55,055,356
Operating loss (31,585,227) (24,925,471) (87,677,020) (54,941,070)
Other (income) expense:        
Interest income (79,163) (87,965) (174,056) (265,456)
Other 29,588 (6,479) 113,281 (96,863)
Total other (income) expense, net (49,575) (94,444) (60,775) (362,319)
Net loss $ (31,535,652) $ (24,831,027) $ (87,616,245) $ (54,578,751)
Basic and diluted net loss per common share $ (0.48) $ (0.50) $ (1.45) $ (1.11)
Weighted average shares used in computing basic and diluted net loss per common share 65,079,128 49,203,277 60,552,084 48,961,582