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RELATED PARTY TRANSACTIONS (Details Narrative)
3 Months Ended 9 Months Ended
Sep. 30, 2017
USD ($)
ft²
shares
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
ft²
shares
Sep. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
shares
Related Party Transaction [Line Items]          
Other research and development $ 25,334,762 $ 20,878,108 $ 71,150,033 $ 45,075,097  
Prepaid Research And Development $ 5,022,846   $ 5,022,846   $ 5,678,755
Common stock issued | shares 70,693,576   70,693,576   56,820,422
LFB License Agreement [] [Member]          
Related Party Transaction [Line Items]          
Other research and development $ 1,800,000 1,900,000 $ 2,300,000 4,300,000  
Accounts Payable 0   0   $ 400,000
Prepaid Research And Development 0   0   1,300,000
Shared Services Agreement [Member]          
Related Party Transaction [Line Items]          
Costs and Expenses, Related Party 300,000 300,000 1,000,000 500,000  
Office Agreement [Member]          
Related Party Transaction [Line Items]          
Accounts Payable 131,000   131,000    
Average Annual Rental Payments $ 1,100,000   $ 1,100,000    
Percentage of Occupancy 45.00%   45.00%    
Area of Land | ft² 24,000   24,000    
Operating Lease, Initial Commitment Period     15 years    
Rent expense     $ 900,000    
Deferred rent $ 1,300,000   1,300,000    
Build out costs     30,000    
JBET Agreement [Member]          
Related Party Transaction [Line Items]          
Accounts Payable $ 200,000   $ 200,000   $ 800,000
Sublicense Fee paid       1,000,000  
Opus [Member]          
Related Party Transaction [Line Items]          
Costs and Expenses, Related Party   $ 20,000   $ 100,000