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Condensed Consolidated Statements of Operations - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Income Statement [Abstract]        
License revenue $ 38,095 $ 38,095 $ 76,190 $ 76,190
Research and development:        
Noncash compensation 1,266,322 567,157 3,572,421 954,082
Other research and development 25,439,477 12,966,574 45,815,271 24,196,989
Total research and development 26,705,799 13,533,731 49,387,692 25,151,071
General and administrative:        
Noncash compensation 223,406 1,081,240 3,912,762 2,393,280
Other general and administrative 1,534,261 1,446,567 2,867,529 2,547,438
Total general and administrative 1,757,667 2,527,807 6,780,291 4,940,718
Total costs and expenses 28,463,466 16,061,538 56,167,983 30,091,789
Operating loss (28,425,371) (16,023,443) (56,091,793) (30,015,599)
Other (income) expense:        
Interest income (50,197) (92,629) (94,893) (177,491)
Other (income) expense (22,090) (31,752) 83,693 (90,384)
Total other (income) expense, net (72,287) (124,381) (11,200) (267,875)
Net loss $ (28,353,084) $ (15,899,062) $ (56,080,593) $ (29,747,724)
Basic and diluted net loss per common share $ (0.45) $ (0.33) $ (0.96) $ (0.61)
Weighted average shares used in computing basic and diluted net loss per common share 63,288,269 48,769,948 58,251,045 48,838,731