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RELATED PARTY TRANSACTIONS (Details Narrative)
3 Months Ended 6 Months Ended
Jun. 30, 2017
USD ($)
ft²
shares
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
ft²
$ / shares
shares
Jun. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
shares
Related Party Transaction [Line Items]          
Other research and development $ 25,439,477 $ 12,966,574 $ 45,815,271 $ 24,196,989  
Prepaid Research And Development $ 9,662,237   $ 9,662,237   $ 5,678,755
Common stock issued | shares 68,127,202   68,127,202   56,820,422
LFB License Agreement [] [Member]          
Related Party Transaction [Line Items]          
Accounts Payable $ 0   $ 0   $ 400,000
Costs and Expenses, Related Party 400,000 2,300,000 500,000 2,300,000  
Prepaid Research And Development $ 1,800,000   $ 1,800,000   1,300,000
Common stock issued | shares 5,000,000   5,000,000    
Warrant to purchase common stock | shares 2,500,000   2,500,000    
Common stock purchase price | $ / shares     $ .001    
Shared Services Agreement [Member]          
Related Party Transaction [Line Items]          
Costs and Expenses, Related Party $ 400,000 $ 200,000 $ 700,000 400,000  
Office Agreement [Member]          
Related Party Transaction [Line Items]          
Accounts Payable 500,000   500,000    
Average Annual Rental Payments $ 1,100,000   $ 1,100,000    
Percentage of Occupancy 45.00%   45.00%    
Area of Land | ft² 24,000   24,000    
Operating Lease, Initial Commitment Period     15 years    
Rent expense     $ 700,000    
Deferred rent $ 1,300,000   1,300,000    
Build out costs     100,000    
JBET Agreement [Member]          
Related Party Transaction [Line Items]          
Accounts Payable 800,000   800,000   $ 800,000
Sublicense Fee paid     $ 1,000,000    
Opus [Member]          
Related Party Transaction [Line Items]          
Costs and Expenses, Related Party $ 20,000     $ 100,000