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Condensed Consolidated Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (27,727,509) $ (13,848,662)
Adjustments to reconcile net loss to net cash used in operating activities:    
Noncash stock compensation expense 5,995,455 1,698,965
Depreciation 20,416 6,380
Amortization of premium on investment securities 30,528 128,329
Change in fair value of notes payable and accrued interest 105,782 (58,632)
Changes in assets and liabilities:    
Increase in restricted cash (1,005) (1,008)
Increase in prepaid research and development and other current assets (3,584,938) (2,250,490)
Decrease (increase) in leasehold interest 19,587 (1,151,163)
Decrease in accrued interest receivable 61,028 21,915
Decrease in other assets 242,372 5,341
Increase (decrease) in accounts payable and accrued expenses 2,551,726 (1,575,974)
Increase in deferred rent 22,289 389,554
Decrease in deferred revenue (38,095) (38,096)
Net cash used in operating activities (22,302,364) (16,673,541)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of equipment 0 (282,261)
Investment in held-to-maturity securities 0 (10,641,270)
Proceeds from maturity of short-term securities 6,000,000 9,000,000
Net cash provided by (used in) investing activities 6,000,000 (1,923,531)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from the exercise of warrants 2,143,084 22,163
Proceeds from sale of common stock, net 84,765,572 0
Deferred financing costs paid 0 (8,000)
Net cash provided by financing activities 86,908,656 14,163
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS 70,606,292 (18,582,909)
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD 25,031,280 55,061,329
CASH AND CASH EQUIVALENTS AT END OF PERIOD 95,637,572 36,478,420
NONCASH TRANSACTIONS    
Reclassification of deferred financing costs to additional paid-in capital (2,645) 0
Accrued financing costs $ 190,709 $ 0