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RELATED PARTY TRANSACTIONS (Details Narrative)
3 Months Ended
Mar. 31, 2017
USD ($)
ft²
$ / shares
shares
Mar. 31, 2016
USD ($)
Dec. 31, 2016
USD ($)
shares
Related Party Transaction [Line Items]      
Other research and development $ 20,375,794 $ 11,230,415  
Prepaid Research And Development $ 8,422,375   $ 5,678,755
Common stock issued | shares 66,816,455   56,820,423
LFB License Agreement [] [Member]      
Related Party Transaction [Line Items]      
Accounts Payable $ 17,000 400,000  
Prepaid Research And Development $ 1,600,000 1,300,000  
Common stock issued | shares 5,000,000    
Warrant to purchase common stock | shares 2,500,000    
Common stock purchase price | $ / shares $ .001    
Shared Services Agreement [Member]      
Related Party Transaction [Line Items]      
Costs and Expenses, Related Party $ 300,000 100,000  
Office Agreement [Member]      
Related Party Transaction [Line Items]      
Accounts Payable 100,000    
Average Annual Rental Payments $ 1,100,000    
Percentage of Occupancy 45.00%    
Area of Land | ft² 24,000    
Operating Lease, Initial Commitment Period 15 years    
Rent expense $ 400,000    
Deferred rent 1,300,000    
JBET Agreement [Member]      
Related Party Transaction [Line Items]      
Accounts Payable 700,000 800,000  
Sublicense Fee paid 1,000,000    
Opus [Member]      
Related Party Transaction [Line Items]      
Costs and Expenses, Related Party $ 0 $ 100,000