LICENSE AGREEMENTS (Details Narrative) - USD ($)	1 Months Ended	12 Months Ended
	Jun. 23, 2014	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2012	Dec. 31, 2013
License Agreement [Line Items]
License revenue		$ 152,381	$ 152,381	$ 152,381
Deferred Revenue		1,371,000	1,524,000	1,676,000	$ 2,000,000	$ 1,829,000
Income taxes		$ 0	0	0
Royalty payment Effective Percentage		6.00%
Maximum sales for royalty expense		$ 1,000,000,000
Other Research and Development Expense		66,489,820	43,445,817	$ 26,004,687
JBET Agreement [Member]
License Agreement [Line Items]
Additional Amount Receivable On Achievement Of Pre Specified Milestones		$ 177,000,000
Opus [Member]
License Agreement [Line Items]
Royalty payment Effective Percentage		1.00%
Common Stock [Member]
License Agreement [Line Items]
Stock Issued During Period, Shares, Issued for Services				496,530
Rhizen [Member]
License Agreement [Line Items]
Payments to Acquire Interest in Joint Venture			$ 4,000,000
Shares, Issued			371,530
Licensing Agreements [Member]
License Agreement [Line Items]
Upfront Fee Received From Sub License					2,000,000
Income taxes					$ 300,000
Stock Issued During Period, Shares, Issued for Services	125,000
Maximum Potential Payments Payable	$ 207,000,000
Royalty payment Effective Percentage	6.00%
Research and Development Expense [Member] | Rhizen [Member]
License Agreement [Line Items]
Non Cash Research And Development Expense			$ 4,100,000
Other Research and Development Expense			$ 4,000,000