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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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Reflects level of percentage of net product cash flow received from the exploitation or commercialization of certain product candidates to repay certain convertible debt.

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No definition available.

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The price per share of the conversion feature embedded in the debt instrument.

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- Definition

The average effective interest rate during the reporting period.

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Period of time between issuance and maturity of debt instrument, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

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- Definition

The fair value of notes issued in noncash investing and financing activities.

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FAIR VALUE MEASUREMENTS (Details Narrative) - USD ($)	1 Months Ended	12 Months Ended
FAIR VALUE MEASUREMENTS (Details Narrative) - USD ($)	Mar. 31, 2010	Dec. 31, 2016	Dec. 31, 2015
Fair Value Measurement [Line Items]
Cumulative Liability		$ 16,700,000	$ 19,900,000
Manhattan and Ariston Pharmaceuticals Merger [Member]
Fair Value Measurement [Line Items]
Notes Issued	$ 15,500,000
Debt Instrument, Convertible, Conversion Price	$ 1,125
Percentage Of Cash Proceeds From Operation To Repay Convertible Debt	5.00%
Debt Instrument, Term	5 years
Debt Instrument, Interest Rate During Period	5.00%
Convertible Notes Payable [Member]
Fair Value Measurement [Line Items]
Cumulative Liability		$ 16,700,000	$ 19,900,000
Debt Instrument, Convertible, Conversion Price		$ 1,125
Debt Instrument, Interest Rate During Period		5.00%	5.00%