ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Significant Accounting Policies [Line Items]
Accumulated deficit	$ (236,386,820)	$ (158,133,926)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	8,033,779	7,064,396	8,890,796
Period Anticipated Sufficient To Fund Operating Cash Flow	24 months
Restricted Cash and Investments	$ 600,000
Prepaid Manufacturing	$ 5,700,000	$ 9,200,000