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QUARTERLY FINANCIAL INFORMATION (Tables)
12 Months Ended
Dec. 31, 2016
Table Text Block Supplement [Abstract]  
Schedule of Quarterly Financial Information
    3 Months Ended

 
    March 31, 2016     June 30, 2016     September 30, 2016     December 31, 2016  
                         
License revenue   $ 38,095     $ 38,095     $ 38,096     $ 38,095  
                                 
Total costs and expenses     14,030,251       16,061,538       24,963,567       24,066,153  
                                 
Net loss   $ (13,848,662 )   $ (15,899,062 )   $ (24,831,027 )   $ (23,674,143 )
                                 
Basic and diluted net loss per common share   $ (0.28 )   $ (0.33 )   $ (0.50 )   $ (0.48 )
                                 

 

    3 Months Ended    
    March 31, 2015     June 30, 2015     September 30, 2015     December 31, 2015  
                         
License revenue   $ 38,095     $ 38,095     $ 38,096     $ 38,095  
                                 
Total costs and expenses     14,640,946       17,149,675       13,863,680       17,678,096  
                                 
Net loss   $ (14,577,735 )   $ (17,103,183 )   $ (13,655,916 )   $ (17,611,812 )
                                 
Basic and diluted net loss per common share   $ (0.35 )   $ (0.38 )   $ (0.28 )   $ (0.37 )