ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
Accumulated deficit	$ 1,527,033,000	$ 1,328,698,000
Cash and cash equivalents, and investment securities	174,100,000
Amount of returns received	600,000
Restricted cash pledge	1,300,000	1,300,000
Impairment to goodwill	0
Prepaid research and development	$ 4,237,000	$ 11,929,000