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Note 9 - License Agreements (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 159 Months Ended
Feb. 10, 2025
Jan. 07, 2025
Jan. 07, 2024
Jul. 28, 2023
Dec. 31, 2012
Mar. 31, 2025
Mar. 31, 2024
Mar. 31, 2025
Dec. 31, 2024
Jan. 31, 2012
Income Tax Expense (Benefit)           $ 408,000 $ 29,000      
Precision BioSciences, Inc. [Member]                    
Investment Purchased Balance Shares (in shares)   220,712 220,712              
Investment Purchased Balance Price Per Share (in dollars per share)     $ 0.77              
License Agreement, Share Price, Trading Days (Day)   30 days                
Maximum [Member] | Precision BioSciences, Inc. [Member]                    
Investment Purchased Balance Shares (in shares)     2,920,816              
L F B License Agreement [Member]                    
License And Collaboration Agreement, Expenses Incurred               $ 31,000,000    
Accounts Payable           0   0    
L F B License Agreement [Member] | License Agreement Terms [Member]                    
Finite-Lived Intangible Asset, Useful Life (Year)                   15 years
Accrued Royalties           12,000,000   12,000,000    
Sublicense Agreement With Ildong Pharmaceutical Co [Member]                    
Upfront Fee Received From Sub License         $ 2,000,000          
Income Tax Expense (Benefit)         300,000          
License Revenue           38,000 38,000      
Deferred Revenue           100,000   100,000 $ 200,000  
Additional Amount Receivable on Achievement of Pre-specified Milestones         $ 5,000,000          
Sublicense Agreement With Ildong Pharmaceutical Co [Member] | License Agreement Terms [Member]                    
Finite-Lived Intangible Asset, Useful Life (Year)         15 years          
Commercialization Agreement With Neuraxpharm [Member]                    
Deferred Revenue           23,700,000   23,700,000    
Additional Amount Receivable on Achievement of Pre-specified Milestones       $ 492,500,000            
License and Collaboration Agreements, One-time, Non-refundable Payment       $ 140,000,000   119,700,000        
Royalty Percentage on Net Product Sales       30.00%            
Agreement Buyback Period (Year)       2 years            
Revenue, Remaining Performance Obligation, Amount           300,000   $ 300,000    
Commercialization Agreement With Neuraxpharm [Member] | Royalty [Member]                    
Revenues           $ 600,000        
Commercialization Agreement With Neuraxpharm [Member] | Royalty [Member] | Maximum [Member]                    
Revenues             $ 100,000      
Briumvi Ublituximab [Member] | Product [Member]                    
Product Sales, Net Related to Performance Obligations       $ 12,500,000            
Precision License Agreement [Member]                    
License Agreement, Amount Paid Upfront     $ 7,500,000              
License Agreement, Amount Paid Upfront, Cash     5,250,000              
License Agreement, Amount Paid Upfront, Equity Investment     2,250,000              
License Agreement, Deferred Payment     $ 2,500,000              
License Agreement, Percentage of Premium on Equity Investment     100.00%              
License Agreement, Share Price, Trading Days (Day)     30 days              
License Agreement, Additional Milestone Payments     $ 288,000,000              
Term After First Commercial Sale (Year)     10 years              
Strategic Platform License Agreement with MaxCyte, Inc. [Member]                    
License Agreement, Amount Paid Upfront $ 1,000,000                  
License Agreement, Additional Milestone Payments 13,000,000                  
Licensing Agreement, Annual License Fee $ 200,000                  
License Agreement, Term (Year) 10 years                  
License Agreement, Renewal Term (Year) 5 years                  
License Agreement, Written Notice Period (Day) 90 days