CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Operating Activities:
Net loss	$ (122,932)	$ (97,941)
Adjustments to reconcile net loss to net cash used in operating activities:
Impairment of long-lived assets	13,235	5,521
Depreciation and amortization	3,961	5,107
Amortization of operating lease right-of-use assets	3,641	4,254
Stock-based compensation	9,079	12,382
Gain on sale of assets classified as held for sale	0	(1,026)
Other	32	57
Net changes in operating assets and liabilities:
Accounts receivable	155	397
Refundable research income tax credits	0	556
Prepaid expenses and other assets	830	4,384
Accounts payable and other accrued liabilities	2,794	(14,169)
Accrued compensation and employee benefits	3,053	5,743
Deferred revenues	(6,657)	13,430
Lease liabilities	(4,047)	(5,579)
Other non-current liabilities	(352)	(255)
Net cash used in operating activities	(97,208)	(67,139)
Investing Activities:
Maturities of marketable securities	0	1,110
Proceeds from sale of marketable securities	0	34,730
Proceeds from sale of assets classified as held for sale	0	1,951
Purchases of property and equipment	(102)	(267)
Net cash (used in) provided by investing activities	(102)	37,524
Financing Activities:
Proceeds from at-the-market offering, net of offering expenses	52,185	7,132
Proceeds from issuance of common stock, net of offering expenses	21,483	21,859
Taxes paid related to net share settlement of equity awards	(3,263)	(904)
Proceeds from issuance of common stock under employee stock purchase plan	344	290
Net cash provided by financing activities	70,749	28,377
Effect of exchange rate changes on cash and cash equivalents and restricted cash	4,091	(2,048)
Net decrease in cash, cash equivalents and restricted cash	(22,470)	(3,286)
Cash, cash equivalents and restricted cash, beginning of period	43,418	46,704
Cash, cash equivalents and restricted cash, end of period	20,948	43,418
Supplemental cash flow disclosures:
Property and equipment included in unpaid liabilities	$ 74	$ 236