CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY (DEFICIT) - USD ($) $ in Thousands	Total	Stock Issuances Excluding At-The-Market Offering	At-The-Market Offering	Common Stock	Common Stock Stock Issuances Excluding At-The-Market Offering	Common Stock At-The-Market Offering	Additional Paid-in Capital	Additional Paid-in Capital Stock Issuances Excluding At-The-Market Offering	Additional Paid-in Capital At-The-Market Offering	Accumulated Deficit	Accumulated Other Comprehensive Loss
Beginning balance (in shares) at Dec. 31, 2023				178,133,548
Beginning balance at Dec. 31, 2023	$ 82,887			$ 1,781			$ 1,492,077			$ (1,406,376)	$ (4,595)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in at-the-market offering, net of offering expenses (in shares)					24,761,905	3,638,740
Issuance of common stock in at-the-market offering, net of offering expenses		$ 21,788	$ 7,132		$ 248	$ 36		$ 21,540	$ 7,096
Issuance of common stock upon exercise of pre-funded warrants (in shares)				3,809,523
Issuance of common stock upon exercise of pre-funded warrants	71			$ 38			33
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)				1,746,271
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax	$ (904)			$ 17			(921)
Issuance of common stock under employee stock purchase plan (in shares)	700,000			747,692
Issuance of common stock under employee stock purchase plan	$ 290			$ 8			282
Stock-based compensation	12,382						12,382
Foreign currency translation adjustment	(2,943)										(2,943)
Net pension gains	241										241
Net unrealized loss on marketable securities, net of tax	(233)										(233)
Net loss	$ (97,941)									(97,941)
Ending balance (in shares) at Dec. 31, 2024	212,837,679			212,837,679
Ending balance at Dec. 31, 2024	$ 22,770			$ 2,128			1,532,489			(1,504,317)	(7,530)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in at-the-market offering, net of offering expenses (in shares)					12,235,000	84,675,406
Issuance of common stock in at-the-market offering, net of offering expenses		$ 21,139	$ 52,185		$ 122	$ 847		$ 21,017	$ 51,338
Issuance of common stock upon exercise of pre-funded warrants (in shares)				34,398,393
Issuance of common stock upon exercise of pre-funded warrants	344			$ 344
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)				5,652,650
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax	$ (3,263)			$ 57			(3,320)
Issuance of common stock under employee stock purchase plan (in shares)	900,000			889,014
Issuance of common stock under employee stock purchase plan	$ 344			$ 9			335
Stock-based compensation	9,079						9,079
Foreign currency translation adjustment	5,975										5,975
Net pension gains	91										91
Net unrealized loss on marketable securities, net of tax	0
Net loss	$ (122,932)									(122,932)
Ending balance (in shares) at Dec. 31, 2025	350,688,142			350,688,142
Ending balance at Dec. 31, 2025	$ (14,268)			$ 3,507			$ 1,610,938			$ (1,627,249)	$ (1,464)