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INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Domestic and Foreign Components of Loss Before Income Taxes
The domestic and foreign components of loss before income taxes were as follows (in thousands):
Year Ended December 31,
20252024
Domestic$(123,969)$(103,729)
Foreign469 5,621 
Loss before income taxes$(123,500)$(98,108)
Schedule of Income Tax Expense (Benefit)
Income tax benefit for the years ended December 31, 2025 and 2024 consisted of the following (in thousands):
Year Ended December 31,
20252024
Income tax benefit:
Current:
Federal$— $— 
State— — 
Foreign(568)(167)
Subtotal(568)(167)
Deferred:
Federal— — 
State— — 
Foreign— — 
Subtotal— — 
Income tax benefit$(568)$(167)
Schedule of Effective Income Tax Rate Reconciliation
The following table represents a reconciliation of the statutory federal rate and the Company’s effective tax rate (after the adoption of ASU 2023-09) for the year ended December 31, 2025 (in thousands):
AmountPercentage
Income taxes (benefit) at statutory federal rate$(25,935)21.0 %
State and local taxes, net of federal income tax effect— — 
Foreign tax effects
Other foreign(667)0.5 %
Effect of cross-border tax laws
Global Intangible Low-taxed Income— — 
Non-taxable or non-deductible items
Other non-taxable or non-deductible items660 (0.5)%
Change in valuation allowance (1)
28,674 (23.2)%
Tax credits
R&D credit(3,671)3.0 %
Changes in unrecognized tax benefits160 (0.1)%
Other adjustments
Other211 (0.2)%
$(568)0.5 %
(1) In 2024, the change in valuation allowance related to the state jurisdictions was included in the change in valuation allowance. In 2025, this amount is net in the state and local taxes.
For the year ended December 31, 2024, prior to the adoption of ASU 2023-09, the effective income tax rate differs from the statutory federal income tax rate as follows (in thousands):
Year Ended December 31,
2024
Tax at federal statutory rate$(20,603)
State taxes, net3,483 
Foreign rate differential263 
Global Intangible Low-taxed Income617 
Non-deductible stock-based compensation2,656 
Research credits(3,201)
Change in valuation allowance16,172 
Other446 
Income tax benefit$(167)
Schedule of Deferred Tax Assets and Liabilities and Based on Tax Jurisdictions Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands):
December 31,
20252024
Assets:
Deferred tax assets:
Net operating loss carryforwards$255,860 $211,585 
Research and development tax credit carryforwards62,819 58,409 
Stock-based compensation4,325 3,998 
Deferred revenue1,476 — 
Capitalized research66,760 74,354 
Property and equipment17,272 15,648 
Intangible assets130 31 
Lease liabilities6,732 6,666 
Accruals and reserves4,754 331 
Other421 235 
Total deferred tax asset420,549 371,257 
Valuation allowance419,779 367,578 
Deferred tax assets770 3,679 
Liabilities:
Operating lease right-of-use assets(770)(3,679)
Deferred tax liabilities(770)(3,679)
Total net deferred tax liabilities$— $— 
Schedule of Unrecognized Tax Benefits Roll Forward
The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands):
December 31,
20252024
Beginning balance$22,137 $18,320 
Additions based on tax positions related to the current year1,292 4,274 
Additions for tax positions of prior years22 26 
Reductions for tax positions of prior years(2,949)(224)
Statute lapse(308)(259)
Ending balance$20,194 $22,137