X0306 4 2018-11-14 0 0001001233 SANGAMO THERAPEUTICS, INC SGMO 0001217456 PARKER H STEWART C/O SANGAMO THERAPEUTICS, INC. POINT RICHMOND TECH CTR, 501 CANAL BLVD. RICHMOND CA 94804 1 0 0 0 Common Stock 2018-11-14 4 P 0 2000 9.0008 A 7500 D Includes 2,500 shares subject to restricted stock units granted on June 11, 2018. The RSUs will fully vest on the earlier of (x) June 11, 2019 (the first anniversary of the date of grant) or (y) the day prior to the 2019 annual stockholders meeting, subject to the Reporting Person's continued service on the Issuer's Board of Directors through such date. /s/ Denise Winn, Attorney-in-Fact for H. Stewart Parker 2018-11-15