X0306 4 2015-12-11 0 0001001233 SANGAMO BIOSCIENCES INC SGMO 0001202278 ANDO DALE G C/O SANGAMO BIOSCIENCES INC. POINT RICHMOND TECH CNTR, 501 CANAL BLVD RICHMOND CA 94804 0 1 0 0 VP, Therapeutic Dev. & CMO Common Stock 2015-12-11 4 F 0 4348 8.68 D 111328 D Common Stock 2015-12-12 4 F 0 4000 8.68 D 107328 D Represents shares withheld by the Issuer to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units. Includes 7,666 and 16,666 shares subject to restricted stock units granted on December 12, 2013 and December 11, 2014 respectively, which will be issued as such units vest in accordance with their terms. /s/ Florence Tam, attorney-in-fact 2015-12-15