X0306 4 2015-12-11 0 0001001233 SANGAMO BIOSCIENCES INC SGMO 0001214505 NICHOL GEOFFREY C/O SANGAMO BIOSCIENCES INC. POINT RICHMOND TECH CNTR, 501 CANAL BLVD RICHMOND CA 94804 0 1 0 0 Executive Vice President, R&D Common Stock 2015-12-11 4 F 0 4697 8.68 D 164060 D Common Stock 2015-12-12 4 F 0 4384 8.68 D 159676 D Represents shares withheld by the Issuer to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units. Includes 11,666 and 25,000 shares subject to restricted stock units granted on December 12, 2013 and December 11, 2014 respectively, that will be issued as such units vest in accordance with their terms. /s/ Florence Tam, attorney-in-fact 2015-12-15