X0306 4 2015-04-06 0 0001001233 SANGAMO BIOSCIENCES INC SGMO 0001238325 RINGO WILLIAM R C/O SANGAMO BIOSCIENCES INC. POINT RICHMOND TECH CNTR, 501 CANAL BLVD RICHMOND CA 94804 1 0 0 0 Common Stock 2015-04-06 4 M 0 2200 6.41 A 3000 D Common Stock 2015-04-06 4 S 0 2200 14.946 D 800 D Stock Option (Right to Buy) 6.41 2015-04-06 4 M 0 2200 0 D 2021-05-31 Common Stock 2200 1200 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 3, 2014, as amended. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.82 to $15.27, inclusive. The Reporting Person undertakes to provide to Sangamo BioSciences, Inc., any security holder of Sangamo BioSciences, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. All shares underlying this option are vested and immediately exercisable. /s/ Florence Tam, Attorney-in-Fact 2015-04-08