X0202 4 2005-02-07 0 0001001233 SANGAMO BIOSCIENCES INC SGMO 0001234386 LANPHIER EDWARD O II C/O SANGAMO BIOSCIENCES INC. STE. 100A POINT RICHMOND TECH CNTR, 501 CANAL BL RICHMOND CA 94804 1 1 0 0 President and CEO Common Stock 200000 D Common Stock 2005-02-07 4 S 0 15000 5.43 D 2232992 I By Trust Common Stock 2005-02-08 4 S 0 5000 5.33 D 2227992 I By Trust Common Stock 100000 I By Trust for Son Common Stock 100000 I By Trust for Daughter Common Stock 100000 I By Trust for Daughter Common Stock 100000 I By Trust for Son The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 7, 2001, as amended on November 7, 2003. These shares are held in the Edward O. Lanphier II and Cameron M. Lanphier Trust U/T/A August 30, 2002, Edward O Lanphier II and Cameron M. Lanphier, Trustees. Reporting Person disclaims beneficial ownership of the shares held by each of his children and this report shall not be deemed to be an admission that Mr. Lanphier is the beneficial owner of such securities for purposes of Section 16 or for any other purpose /s/ Edward O. Lanphier II 2005-02-09