X0306 4 2022-08-29 0 0001001233 SANGAMO THERAPEUTICS, INC SGMO 0000875045 BIOGEN INC. 225 BINNEY ST. CAMBRIDGE MA 02142 0 0 1 0 0001810387 Biogen MA Inc. 225 BINNEY ST. CAMBRIDGE MA 02142 0 0 1 0 Common Stock 2022-08-29 4 S 0 400000 5.3268 D 23752466 I By Biogen MA Inc. Common Stock 2022-08-30 4 S 0 100000 5.2652 D 23652466 I By Biogen MA Inc. The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.205 to $5.475, inclusive. The reporting person undertakes to provide to Sangamo Therapeutics, Inc., any security holder of Sangamo Therapeutics, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Shares are owned indirectly by Biogen Inc. and directly by its wholly-owned subsidiary Biogen MA Inc. The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.1235 to $5.49, inclusive. The reporting person undertakes to provide to Sangamo Therapeutics, Inc., any security holder of Sangamo Therapeutics, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. BIOGEN INC. By: /s/ Michael Dambach, Vice President and Treasurer 2022-08-31 BIOGEN MA INC. By: /s/ Michael Dambach, Vice President and Treasurer 2022-08-31