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Income Taxes - Tax Rates (Details)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Taxes      
Statutory federal tax rate (21.00%) (21.00%) (34.00%)
State income taxes, net of federal benefit (2.00%) (3.00%) (3.00%)
Research and development and other tax credits (3.00%) (3.00%) (2.00%)
Other 1.00% 1.00% (1.00%)
Change in tax rate 3.00% 5.00% 70.00%
Change in valuation allowance 22.00% 21.00% (30.00%)
Income tax provision 0.00% 0.00% 0.00%