X0306 4 2022-03-04 0 0001000228 HENRY SCHEIN INC HSIC 0001194353 PALADINO STEVEN C/O HENRY SCHEIN, INC. 135 DURYEA ROAD MELVILLE NY 11747 1 1 0 0 EVP, Chief Financial Officer Common Stock, par value $0.01 per share 2022-03-04 4 D 0 685 0.00 D 138972 D Common Stock, par value $0.01 per share 2022-03-04 4 F 0 9351 86.98 D 129621 D Common Stock, par value $0.01 per share 6683 I By 401(k) Represents the surrender of shares to the Issuer to satisfy the reporting person's tax withholding obligation upon the vesting of the reporting person's March 5, 2019 grant of performance-based restricted stock/units. (Actual vesting date of March 5, 2022 was a non-business day so vesting occurred on the preceding business day.) Reflects the reporting person's interest in equivalent shares of Henry Schein common stock held by the unitized stock fund in the Henry Schein, Inc. 401(k) Savings Plan (the "Plan"). The unitized stock fund consists of Henry Schein common stock and cash or cash equivalents. The number of shares attributed to the reporting person as a participant in the Plan and expressed as equivalent shares has been calculated based on the closing price of Henry Schein common stock on March 4, 2022. /s/ Jennifer Ferrero (as Attorney-in-Fact for Steven Paladino) 2022-03-08