Exhibit 99.3

 

Pharvaris N.V.

Unaudited Condensed Consolidated Interim Financial Statements

For the six months ended June 30, 2025

 

 

 


 

Contents

 

Unaudited condensed consolidated statement of loss and other comprehensive (loss) /income

3

 

 

Unaudited condensed consolidated statement of financial position

4

 

 

Unaudited condensed consolidated statement of changes in equity

5

 

 

Unaudited condensed consolidated statement of cash flows

6

 

 

Notes to the unaudited condensed consolidated interim financial statements

7

 

 

 

 

2


 

Unaudited condensed consolidated statement of loss and other comprehensive (loss) /income

 

 

 

 

Three months ended June 30,

 

Six months ended June 30,

 

 

 

 

2025

 

2024

 

2025

 

2024

 

 

Notes

 

 

 

 

 

Research and development expenses

 

3

 

 

(29,607,908

)

 

(23,067,934

)

 

(60,522,301

)

 

(41,580,950

)

General and administrative expenses

 

4

 

 

(10,765,189

)

 

(11,314,067

)

 

(22,037,107

)

 

(21,112,910

)

Total operating expenses

 

 

 

(40,373,097

)

 

(34,382,001

)

 

(82,559,408

)

 

(62,693,860

)

Finance (expense)/income

 

6

 

 

(4,904,807

)

 

4,721,551

 

 

(8,756,652

)

 

5,299,771

 

Loss before income tax

 

 

 

(45,277,904

)

 

(29,660,450

)

 

(91,316,060

)

 

(57,394,089

)

Income taxes

 

7

 

 

(202,782

)

 

(70,623

)

 

(505,449

)

 

(355,740

)

Net Loss

 

 

 

(45,480,686

)

 

(29,731,073

)

 

(91,821,509

)

 

(57,749,829

)

Other comprehensive (loss) income

 

 

 

 

 

 

 

 

 

 

Items that may be reclassified to profit or loss:

 

 

 

 

 

 

 

 

 

 

Exchange (losses) gains arising on translation of foreign operations

 

 

 

(261,162

)

 

21,106

 

 

(389,917

)

 

56,739

 

Total comprehensive loss attributable to:

 

 

 

 

 

 

 

 

 

 

Equity holders of the Company

 

 

 

(45,741,848

)

 

(29,709,967

)

 

(92,211,426

)

 

(57,693,090

)

Loss per share attributable to the equity holders of the Company during the periods

 

 

 

 

 

 

 

 

 

Basic and diluted loss per share:

19

 

 

(0.83

)

 

(0.55

)

 

(1.68

)

 

(1.07

)

 

The accompanying notes are an integral part of these unaudited condensed consolidated interim financial statements.

 

3


 

Unaudited condensed consolidated statement of financial position

 

 

 

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

Notes

 

 

 

 

 

Assets

 

 

 

 

 

 

 

 

 

Non-current assets

 

 

 

 

 

 

 

 

 

Property, plant and equipment

 

 

8

 

 

 

719,994

 

 

 

667,000

 

Right of use assets

 

 

9

 

 

 

618,613

 

 

 

813,842

 

Deferred tax assets

 

 

7

 

 

 

297,873

 

 

 

474,347

 

Current assets

 

 

 

 

 

 

 

 

 

Receivables

 

 

10

 

 

 

531,640

 

 

 

457,834

 

Other current assets

 

 

11

 

 

 

6,004,953

 

 

 

5,747,025

 

Cash and cash equivalents

 

 

12

 

 

 

199,571,685

 

 

 

280,728,037

 

Current tax receivable

 

 

10

 

 

 

2,065,568

 

 

 

2,486,680

 

Total assets

 

 

 

 

 

209,810,326

 

 

 

291,374,765

 

 

 

 

 

 

 

 

 

 

Equity and liabilities

 

 

 

 

 

 

 

 

 

Equity

 

 

 

 

 

 

 

 

 

Share capital

 

 

13

 

 

 

6,568,445

 

 

 

6,525,539

 

Share premium

 

 

 

 

 

628,674,864

 

 

 

623,641,380

 

Other reserves

 

 

 

 

 

44,289,200

 

 

 

39,711,103

 

Currency translation reserve

 

 

 

 

 

(252,191

)

 

 

137,726

 

Accumulated loss

 

 

 

 

 

(494,944,426

)

 

 

(402,255,007

)

Total equity

 

 

 

 

 

184,335,892

 

 

 

267,760,741

 

 

 

 

 

 

 

 

 

 

Long term liabilities

 

 

 

 

 

 

 

 

 

Non-current lease liability

 

 

9

 

 

 

472,606

 

 

 

639,043

 

Current liabilities

 

 

 

 

 

 

 

 

 

Trade and other payables

 

 

14

 

 

 

4,859,249

 

 

 

4,562,900

 

Accrued liabilities

 

 

15

 

 

 

19,400,357

 

 

 

17,588,407

 

Current lease liability

 

 

9

 

 

 

161,544

 

 

 

222,427

 

Current tax payable

 

 

 

 

 

580,678

 

 

 

601,247

 

Total liabilities

 

 

 

 

 

25,474,434

 

 

 

23,614,024

 

Total equity and liabilities

 

 

 

 

 

209,810,326

 

 

 

291,374,765

 

 

The accompanying notes are an integral part of these unaudited condensed consolidated interim financial statements.

 

 

4


 

Unaudited condensed consolidated statement of changes in equity

For the six months ended June 30, 2025 and June 30, 2024

 

 

 

 

 

 

 

Share
capital

 

 

Share
premium

 

 

Other
reserves

 

 

Currency
translation
reserve

 

 

Accumulated
losses

 

 

Total
Equity

 

 

 

Notes

 

 

 

 

 

 

 

 

 

 

 

 

 

Balance at January 1, 2024

 

 

 

 

 

6,274,833

 

 

 

615,811,986

 

 

 

27,894,796

 

 

 

(14,584

)

 

 

(265,918,628

)

 

 

384,048,403

 

Net Loss

 

 

 

 

 

 

 

 

 

(57,749,829

)

 

 

(57,749,829

)

Issue of share capital

 

 

 

 

 

165,000

 

 

(165,000

)

 

12,609

 

 

 

 

 

12,609

 

Transaction costs on issue of shares

 

 

 

 

 

 

592,000

 

 

 

 

 

 

592,000

 

Currency translation reserve

 

 

 

 

 

 

 

 

56,739

 

 

 

 

56,739

 

Share-based payments

 

 

18

 

 

 

 

 

 

6,288,303

 

 

 

 

 

 

6,288,303

 

Settlement of share-based payments

 

 

 

 

 

41,092

 

 

 

2,808,656

 

 

 

(2,230,060

)

 

 

 

 

 

(1,099,188

)

 

 

(479,500

)

Balance at June 30, 2024

 

 

 

 

 

6,480,925

 

 

 

619,047,642

 

 

 

31,965,648

 

 

 

42,155

 

 

 

(324,767,645

)

 

 

332,768,725

 

Balance at January 1, 2025

 

 

 

 

 

6,525,539

 

 

 

623,641,380

 

 

 

39,711,103

 

 

 

137,726

 

 

 

(402,255,007

)

 

 

267,760,741

 

Net Loss

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(91,821,509

)

 

 

(91,821,509

)

Currency translation reserve

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(389,917

)

 

 

 

 

 

(389,917

)

Settlement of share-based payments

 

 

 

 

 

42,906

 

 

 

5,033,484

 

 

 

(5,046,933

)

 

 

 

 

 

(867,910

)

 

 

(838,453

)

Share-based payments

 

 

18

 

 

 

 

 

 

 

 

 

9,625,030

 

 

 

 

 

 

 

 

 

9,625,030

 

Balance at June 30, 2025

 

 

 

 

 

6,568,445

 

 

 

628,674,864

 

 

 

44,289,200

 

 

 

(252,191

)

 

 

(494,944,426

)

 

 

184,335,892

 

 

The accompanying notes are an integral part of these unaudited condensed consolidated interim financial statements.

 

5


 

Unaudited condensed consolidated statement of cash flows

For the six months ended June 30, 2025 and 2024

 

 

 

 

 

 

2025

 

 

2024

 

 

 

Notes

 

 

 

 

Operating activities

 

 

 

 

 

 

 

 

Loss before tax

 

 

 

 

(91,316,060

)

 

 

(57,394,089

)

Non-cash adjustments to reconcile loss before tax to net cash flows from operations:

 

 

 

 

 

 

 

 

Share-based payment expense

 

18

 

 

9,625,030

 

 

 

6,288,303

 

Depreciation expense

 

4

 

 

208,333

 

 

 

135,032

 

Net foreign exchange loss (gain)

 

6

 

 

12,001,515

 

 

 

(3,146,528

)

Finance income

 

6

 

 

(438,896

)

 

 

(2,160,801

)

 

 

 

 

 

 

 

 

Changes in working capital:

 

 

 

 

 

 

 

 

(Increase) in receivables

 

 

 

 

(73,806

)

 

 

(91,786

)

Increase in other current assets

 

 

 

 

(383,606

)

 

 

(300,336

)

Increase trade and other payables

 

 

 

 

422,029

 

 

 

58,721

 

Increase in accrued liabilities

 

 

 

 

942,596

 

 

 

3,690,913

 

 

 

 

 

 

 

 

 

 

Income taxes received (paid)

 

 

 

 

98,343

 

 

 

(1,114,758

)

Received interest

 

 

 

 

462,559

 

 

 

2,120,352

 

Net cash flows used in operating activities

 

 

 

 

(68,451,963

)

 

 

(51,914,977

)

 

 

 

 

 

 

 

 

Investing activities

 

 

 

 

 

 

 

 

Purchase of property, plant and equipment

 

8

 

 

(144,367

)

 

 

(70,844

)

Net cash flows used in investing activities

 

 

 

 

(144,367

)

 

 

(70,844

)

 

 

 

 

 

 

 

 

Financing activities

 

 

 

 

 

 

 

 

Proceeds from issue of shares

 

13

 

 

29,458

 

 

 

632,737

 

Transaction costs on issue of shares, net

 

 

 

 

 

 

 

592,968

 

Payment of principal portion of lease liabilities

 

9

 

 

(127,805

)

 

 

(107,239

)

Net cash flows (used in) provided by financing activities

 

 

 

 

(98,347

)

 

 

1,118,466

 

 

 

 

 

 

 

 

 

Net decrease in cash and cash equivalents

 

 

 

 

(68,694,677

)

 

 

(50,867,355

)

Cash and cash equivalents at the beginning of the period

 

 

 

 

280,728,037

 

 

 

391,231,637

 

Effect of exchange rate changes

 

 

 

 

(12,461,675

)

 

 

3,210,104

 

Cash and cash equivalents at the end of the period

 

12

 

 

199,571,685

 

 

 

343,574,386

 

 

The accompanying notes are an integral part of these unaudited condensed consolidated interim financial statements.

6


 

Notes to the unaudited condensed consolidated interim financial statements

1. Corporate and Group information

This section provides general corporate and group information about Pharvaris N.V. and its subsidiaries.

1.1 Corporate information

Pharvaris N.V. was incorporated on September 30, 2015 and is based in Leiden, the Netherlands.

The Company’s registered office is located at Emmy Noetherweg 2, Leiden. The Company is registered at the Chamber of Commerce under file number 64239411.

Pharvaris is a late-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for rare diseases with significant unmet need, initially focused on angioedema and other bradykinin-mediated diseases.

The unaudited condensed consolidated interim financial statements of Pharvaris N.V. (the “Company” or “Pharvaris”) and its subsidiaries (collectively, “The Group”) as of June 30, 2025, and December 31, 2024, and for the three and six months ended June 30, 2025 and 2024 were authorized for issue in accordance with a resolution of the directors on August 12, 2025.

1.2 Group information

Subsidiaries

The unaudited condensed consolidated interim financial statements of the Group include:

 

 

 

 

 

Country of

 

% of equity interest as
June 30,

Name

 

Legal seat

 

incorporation

 

2025

 

2024

Pharvaris Holdings B.V.

 

Leiden

 

The Netherlands

 

100%

 

100%

Pharvaris Netherlands B.V.

 

Leiden

 

The Netherlands

 

100%

 

100%

Pharvaris GmbH

 

Zug

 

Switzerland

 

100%

 

100%

Pharvaris, Inc.

 

Delaware

 

United States of America

 

100%

 

100%

Pharvaris Pharmaceuticals, Inc.*

 

Delaware

 

United States of America

 

100%

 

NA

*Pharvaris Pharmaceuticals, Inc was incorporated in June 2025

The ultimate parent company of the Group is Pharvaris N.V., which is based in the Netherlands.

 

 

2. Summary of significant accounting policies

2.1 Basis of preparation

The unaudited condensed consolidated interim financial statements have been prepared in accordance with IAS 34 Interim Financial Reporting as issued by the International Accounting Standards Board (IASB) and should be read in conjunction with the Group’s annual consolidated financial statements for the year ended December 31, 2024 (“last annual financial statements”). These unaudited condensed consolidated interim financial statements do not include all the information required for a complete set of financial statements prepared in accordance with IFRS as issued by the IASB.

However, selected explanatory notes are included to explain events and transactions that are significant to an understanding of the changes in the Group’s financial position and performance since the last annual financial statements.

The unaudited condensed consolidated interim financial statements have been prepared on a historical cost basis. Unless otherwise stated, the unaudited condensed consolidated interim financial statements are presented in euros and all values are rounded to the nearest EUR (€), except per share amounts.

During the six-month period ended June 30, 2025, the Company undertook a review of its expense classification methodology to better align with the nature of the underlying activities and industry practices. As a result of this review, certain personnel, consulting, and facility related costs previously reported under General and Administrative expenses were determined to be more appropriately classified as Research and Development expenses. The Company reclassified approximately €0.5 million and €0.7 million from General and Administrative expenses to Research and Development expenses for the three and six months ending, June 30, 2025, respectively. This reclassification had no impact on the total operating expenses, net loss, or loss per share.

 

7


 

2.2 Going concern

 

Management assessed the Company’s ability to fund its operations for a period of at least 12 months after the date of signing these financial statements. Management has not identified significant going concern risks. The financial statements of the Company have been prepared on the basis of the going concern assumption based on its existing funding, taking into account the Company’s current cash position and the projected cash flows based on the activities under execution on the basis of Pharvaris’ business plan and budget.

 

2.3 Use of judgements and estimates

In preparing these unaudited condensed consolidated interim financial statements, management has made judgements and estimates that affect the application of accounting policies and the reported amounts of assets and liabilities, income and expense. Actual results may differ from these estimates.

The significant judgements made by management in applying the Group’s accounting policies and the key sources of estimation uncertainty were the same as those described in the last annual financial statements.

2.4 Change in material accounting policies

The accounting policies applied in these unaudited condensed consolidated interim financial statements are the same as those applied in the consolidated financial statements for the year ended December 31, 2024.

Effective Standards

IASB’s Amendments to IAS 21 — Lack of Exchangeability (issued May 2024, effective for annual reporting periods beginning on or after 1 January 2025) provide guidance on how to determine the spot exchange rate when a currency is not exchangeable into another currency. An entity applies the amendments for annual reporting periods beginning on or after 1 January 2025. The Group has evaluated that there is no impact on the company due to this amendment.

New standards and interpretations issued not yet effective

In April 2024, the IASB issued IFRS 18 Presentation and Disclosure in Financial Statements (“IFRS 18”) which replaces IAS 1 Presentation of Financial Statements. IFRS 18 requires an entity to classify all income and expenses within its statement of profit or loss into one of five categories: operating; investing; financing; income taxes; and discontinued operations. The first three categories are new. These categories are complemented by the requirement to present subtotals and totals for “operating profit or loss”, “profit or loss before financing income and taxes” and “profit or loss”. IFRS 18, and the amendments to the other standards, is effective for reporting periods beginning on or after January 1, 2027, but earlier application is permitted. The Group is currently evaluating the impact of this amendment.

There are no other IFRS or IFRIC interpretations that are not yet effective and that are expected to have a material impact to the interim consolidated financial statements.

3. Research and development expenses

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Clinical expenses

 

 

(14,712,960

)

 

(15,065,644

)

 

(32,049,342

)

 

(22,387,056

)

Personnel expenses (Note 5)

 

 

(9,351,648

)

 

(6,450,500

)

 

(17,777,098

)

 

(11,630,976

)

Nonclinical expenses

 

 

(2,858,075

)

 

130,020

 

 

(4,708,265

)

 

(1,705,446

)

Manufacturing costs

 

 

(2,571,095

)

 

(1,572,017

)

 

(5,799,627

)

 

(4,135,971

)

License costs

 

 

 

 

 

 

 

 

(1,500,000

)

Intellectual Property costs

 

 

(114,130

)

 

(109,793

)

 

(187,969

)

 

(221,501

)

 

 

 

(29,607,908

)

 

(23,067,934

)

 

(60,522,301

)

 

(41,580,950

)

 

Development expenses are currently not capitalized but are recorded in the condensed consolidated statements of profit or loss and other comprehensive loss because the recognition criteria for capitalization are not met.

Clinical expenses include costs of conducting and managing our sponsored clinical trials, including clinical investigator cost, costs of clinical sites, and costs for CRO’s assisting with our clinical development programs and travel expenses.

Manufacturing expenses include costs related to manufacturing of active pharmaceutical ingredients and manufacturing of the products used in our clinical trials and research and development activities as well as travel expenses.

8


 

Nonclinical expenses include costs of our outsourced discovery and nonclinical development studies and associated travel expenses.

 

Licensing costs consist of milestone payments reflecting the start of the Phase III study.

 

4. General and administrative expenses

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Personnel expenses (Note 5)

 

 

(5,775,619

)

 

(4,407,998

)

 

(10,804,858

)

 

(7,678,193

)

Professional fees

 

 

(1,686,774

)

 

(2,155,727

)

 

(4,290,920

)

 

(3,332,956

)

Facilities, communication & office expenses

 

 

(1,389,322

)

 

(1,466,955

)

 

(2,740,083

)

 

(3,147,222

)

Accounting, tax and auditing fees

 

 

(743,906

)

 

(850,599

)

 

(1,361,229

)

 

(2,104,685

)

Travel expenses

 

 

(274,070

)

 

(399,111

)

 

(599,201

)

 

(1,023,140

)

Consulting fees

 

 

(28,497

)

 

(732,951

)

 

(76,065

)

 

(859,476

)

Other expenses

 

 

(867,001

)

 

(1,300,726

)

 

(2,164,751

)

 

(2,967,238

)

 

 

 

(10,765,189

)

 

(11,314,067

)

 

(22,037,107

)

 

(21,112,910

)

 

Since 2022, the Group entered into a number of short-term rental arrangements, the expenses are included in "Other expenses".

Depreciation expense for the six months ended June 30, 2025 and 2024 was €0.2 million and 0.1 million, which related to property, plant and equipment and leases and is included in the 'Other expenses' line.

5. Personnel expenses

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Wages and salaries

 

 

(8,053,043

)

 

(5,953,069

)

 

(15,955,350

)

 

(11,023,525

)

Share-based payments

 

 

(5,497,118

)

 

(3,887,436

)

 

(9,625,030

)

 

(6,288,303

)

Other social security charges

 

 

(915,557

)

 

(660,711

)

 

(1,626,736

)

 

(1,245,426

)

Pension charges

 

 

(589,441

)

 

(357,282

)

 

(1,134,157

)

 

(751,915

)

Other employee related costs

 

 

(72,108

)

 

 

 

(240,683

)

 

 

 

 

 

(15,127,267

)

 

(10,858,498

)

 

(28,581,956

)

 

(19,309,169

)

 

The average number of staff (in FTEs) employed by the Group in the six months ended June 30, 2025 was 114 (2024: 83).

6. Finance (expense)/ income

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Foreign exchange differences

 

 

(5,867,219

)

 

2,616,719

 

 

(10,889,757

)

 

3,138,970

 

Interest and other income over bank balances

 

 

1,000,543

 

 

2,114,635

 

 

2,197,192

 

 

2,178,556

 

Other finance expenses

 

 

(38,131

)

 

(9,803

)

 

(64,087

)

 

(17,755

)

 

 

 

(4,904,807

)

 

4,721,551

 

 

(8,756,652

)

 

5,299,771

 

 

7. Income taxes

Income taxes are accounted for in line with IAS 34. The interim period is considered part of a larger financial year, where the income tax is recognized in each interim period based on the best estimate of the weighted average annual

9


 

income tax rate expected for the full financial year. The estimated tax expenses are determined based on a full-year basis (P&L) and subsequently allocated using the expected full year effective tax rate. The discrete items are recognized in full in the interim period in which they emerge. In the total interim tax charge, no distinction is made between current and deferred tax expenses/ income.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

For the three months ended June 30,

 

 

For the six months ended June 30,

 

 

 

2025

 

 

2024

 

 

2025

 

 

2024

 

 

 

 

 

 

 

 

 

 

Income tax expense

 

 

(157,772

)

 

 

(70,623

)

 

 

(374,921

)

 

 

(355,740

)

Deferred tax charge

 

 

(45,010

)

 

 

 

 

 

(130,528

)

 

 

 

Income tax expense

 

 

(202,782

)

 

 

(70,623

)

 

 

(505,449

)

 

 

(355,740

)

 

The tax expense over the three and six months ended June 30, 2025 and 2024 relates to the Company's U.S. and Dutch subsidiaries as the result of a cost-plus agreement between the Company's principal entity and the U.S. and the Dutch subsidiaries, resulting in an estimated taxable profit in the U.S. and the Netherlands.

Reconciliation of income tax benefit at statutory tax rate and the income tax expense as reported in the unaudited condensed consolidated statement of profit or loss and other comprehensive income is as follows:

 

 

 

For the three months ended June 30,

 

For the six months ended
 June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Loss before income tax

 

 

(45,277,904

)

 

(29,660,450

)

 

(91,316,060

)

 

(57,394,089

)

Income tax at statutory income tax rate in the Netherlands (25.8%)

 

 

11,681,699

 

 

7,652,396

 

 

23,559,543

 

 

14,807,675

 

Effect of tax rates in other countries

 

 

(6,368,484

)

 

(4,260,352

)

 

(12,922,011

)

 

(8,412,880

)

Deferred tax assets recognition effects

 

 

(5,236,870

)

 

(3,224,214

)

 

(10,536,949

)

 

(6,007,203

)

Non-deductible expenses

 

 

(186,549

)

 

(238,743

)

 

(515,860

)

 

(573,609

)

Transfer Pricing adjustment

 

 

(43,987

)

 

 

 

(43,987

)

 

 

Prior period adjustments

 

 

(48,591

)

 

290

 

 

(46,185

)

 

(169,723

)

Income tax expense

 

 

(202,782

)

 

(70,623

)

 

(505,449

)

 

(355,740

)

 

Income tax expense is recognized based on management’s estimate of the weighted average effective annual income tax rate expected for the full financial year, bearing in mind the impact of non-discrete and discrete items. Non discrete items in the income tax expense are recognized based on management’s estimate of the weighted average effective annual income tax rate expected for the full financial year. Discrete items in the income tax expense are recognized at the applicable statutory tax rate.

The (estimated) average annual tax rate used for the six months ended June 30, 2025 was 0.55%, compared to 0.62% for the six months ended June 30, 2024.

The current period losses for which no deferred tax asset has been recognized mainly consists of the unrecognized tax effect of losses incurred in Switzerland. The differences in the overseas tax rates are due to the lower tax rate in Switzerland compared to the statutory income tax rate in the Netherlands.

Pharvaris N.V. is the head of the fiscal unity including Pharvaris Netherlands B.V. and Pharvaris Holdings B.V.

Deferred tax

Deferred taxes have been recognized to the extent that management concludes that there is sufficient probability as per IAS 12 that there will be future taxable profits available in the foreseeable future against which the unused tax losses and deductible temporary differences can be utilized.

Deferred tax assets relating to losses carried forward have not been recognized, and deferred tax assets on deductible temporary differences in excess of deferred tax liabilities on taxable temporary differences have not been recognized in the consolidated statement of profit and loss and other comprehensive income for the Dutch fiscal unity.


8. Property, plant and equipment

10


 

 

 

 

June 30, 2025

 

 

December 31, 2024

 

Net book value

 

 

 

 

Balance at beginning of period

 

 

667,000

 

 

 

223,678

 

Additions

 

 

144,367

 

 

 

538,085

 

Depreciation expenses

 

 

(91,373

)

 

 

(94,763

)

Balance at end of period

 

 

719,994

 

 

 

667,000

 

 

 

 

 

 

 

 

 

 

June 30, 2025

 

 

December 31, 2024

 

Cumulative depreciation

 

 

 

 

As of January 1,

 

 

(220,136

)

 

 

(125,373

)

Depreciation

 

 

(91,373

)

 

 

(94,763

)

Balance at end of period

 

 

(311,509

)

 

 

(220,136

)

 

 

 

 

 

 

 

 

 

June 30, 2025

 

 

December 31, 2024

 

Cumulative Costs

 

 

 

 

Balance at beginning of period

 

 

887,136

 

 

 

349,051

 

Additions

 

 

144,367

 

 

 

538,085

 

Balance at end of period

 

 

1,031,503

 

 

 

887,136

 

 

During the six months ended June 30, 2025, the Group acquired assets with a cost of €0.1 million (December 31, 2024: €0.5 million). The acquisitions were mainly related to equipment, tools and installations.

9. Leases

The following table provides information about the Group’s right-of-use assets:

 

 

 

June 30,
2025

 

 

December 31, 2024

 

 

 

 

 

 

Balance at beginning of period

 

 

813,842

 

 

 

231,893

 

Addition

 

 

25,735

 

 

 

756,748

 

Depreciation charges

 

 

(116,960

)

 

 

(174,799

)

Impact of transaction of foreign currency

 

 

(104,004

)

 

 

 

Balance at end of period

 

 

618,613

 

 

 

813,842

 

 

The following table provides information about the Group’s lease liabilities at June 30, 2025:

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

 

 

 

Office leases

 

 

(634,150

)

 

 

(861,470

)

Total lease liability

 

 

(634,150

)

 

 

(861,470

)

Current portion

 

 

(161,544

)

 

 

(222,427

)

Non-current portion

 

 

(472,606

)

 

 

(639,043

)

 

Office leases consist of (i) a lease that was entered into on December 1, 2022 with an expiration date of November 30, 2025 for offices in Leiden, the Netherlands, and (ii) a new lease agreement entered into on October 16, 2024 with an expiration date of December 31, 2029, for office space in Lexington, Massachusetts, United States of America (the "U.S.").

 

On June 30, 2024 a lease related to office space in Lexington, Cranberry One Suite 300, expired.

 

The average incremental borrowing rate applied to the lease liability related to the Leiden lease was 7.77% during the six months ended June 30, 2025 and the twelve months ended December 31, 2024.

 

11


 

The average incremental borrowing rate applied to the lease liability related to the U.S. lease was 6.39% for the year ended six months ended June 30, 2025 and the twelve months ended December 31, 2024.

Depreciation expense was €0.1 million for each of the six months ended June 30, 2025 and 2024, and is reflected in general and administrative expenses as determined by the underlying activities.

 

The total expense related to short-term and low-value leases for the six months ended June 30, 2025 and 2024, was €0.1 million and €0.1 million, respectively, and is included in facility, communication, and office expenses.

 

Cash outflows related to leases during the six months ended June 30, 2025 and 2024 were €0.1 million and €0.1 million, respectively.

10. Receivables

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

 

 

 

Current tax receivable

 

 

2,065,568

 

 

 

2,486,680

 

VAT receivables

 

 

531,640

 

 

 

457,834

 

 

 

 

2,597,208

 

 

 

2,944,514

 

 

11. Other current assets

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

 

 

 

Prepayments

 

 

6,004,953

 

 

 

5,747,025

 

 

 

 

6,004,953

 

 

 

5,747,025

 

 

Prepayments mainly relate to prepaid insurance, prepaid research and development expenses and rent.

 

12. Cash and cash equivalents

As of June 30, 2025 and December 31, 2024, there were no restricted cash and cash equivalent balances. Cash and cash equivalent balances as of June 30, 2025 include investments in money market funds of 95.7 million at fair market value. (Cost: 95.7 million) (December 31, 2024: Euro nil).

 

13. Equity

On June 30, 2025, the Company’s authorized share capital amounted to € 14.1 million divided into 117,500,000 ordinary shares each with a nominal value of twelve eurocents (€0.12).

As of June 30, 2025, the total number of issued and fully paid shares was 54,737,043 (2024: 54,007,711). On June 30, 2025, the issued share capital totaled 6.6 million (2024: 6.5 million).

 

In March 2022, the Company filed a Form F-3 Registration Statement and prospectus, allowing the Company to sell up to $350 million of its securities with the Securities and Exchange Commission. This Registration Statement was supplemented by a prospectus supplement covering an at-the-market program providing for the sales from time to time of up to $75 million of its ordinary shares pursuant to a Sales Agreement with Leerink Partners.

 

As of June 30, 2025, the Company has sold a total of 593,927 ordinary shares under the sales agreement generating total net proceeds of $9.8 million (€9.3 million), after deducting $0.3 million (€0.3 million), which was payable to Leerink Partners as commission in respect of such sales. On April 12, 2024, the Company terminated the March 2022 sales agreement and entered into a new sales agreement with Leerink Partners (the “April 2024 Sales Agreement”), pursuant to which it may sell ordinary shares having an aggregate offering price of up to $175 million from time to time through Leerink Partners. In April 2024, the Company filed a Form F-3 ASR Registration Statement (the “F-3 ASR”) and prospectus, allowing the Company to sell an unspecified amount of its securities with the Securities and Exchange Commission. The F-3 ASR was supplemented by a prospectus supplement covering an at-the-market program providing for the sales from time to time of up to $175 million of its ordinary shares pursuant to the April 2024 Sales Agreement.

12


 

In June 2023, the Company sold a total of 6,951,340 ordinary shares, par value €0.12 per share, in a private placement at a purchase price of $10.07 per ordinary share. The sale generated total proceeds of approximately $70 million (€64.2 million).

In December, 2023, the Company entered into an underwriting agreement with Morgan Stanley & Co. LLC and Leerink Partners, LLC as underwriters, pursuant to which the Company agreed to issue and sell (i) 11,125,000 ordinary shares, par value €0.12 per share and (ii) pre-funded warrants to purchase up to 1,375,000 ordinary shares in an underwritten offering. The offering closed on December 8, 2023, and the Company generated net proceeds of $282.0 million (€261.6 million), after deducting bank fees of $18.0 million (€16.7 million).

The pre-funded warrants were exercised in January 2024 for gross exercise proceeds of $0.01 million and resulted in issuance of 1,375,000 ordinary shares.

In March 2024, the Company received a partial reimbursement for certain of its expenses in connection with the December 2023 offering which have been accounted for in the share premium.

 

Issued shares

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

Number of shares

 

 

Number of shares

 

Ordinary shares

 

 

54,737,043

 

 

 

54,379,491

 

 

 

 

54,737,043

 

 

 

54,379,491

 

 

14. Trade and other payables

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

 

 

 

Trade payables

 

 

4,859,249

 

 

 

4,562,900

 

 

 

 

4,859,249

 

 

 

4,562,900

 

 

15. Accrued liabilities

 

 

 

June 30,
2025

 

 

December 31,
2024

 

 

 

 

 

 

Clinical accrued liabilities

 

 

7,950,639

 

 

 

5,221,572

 

Personnel related accruals

 

 

6,387,541

 

 

 

7,827,392

 

Manufacturing accrued liabilities

 

 

3,204,474

 

 

 

1,767,291

 

Nonclinical accrued liabilities

 

 

331,605

 

 

 

445,238

 

Consulting, professional and audit liability

 

 

238,400

 

 

 

729,162

 

Other accrued liabilities

 

 

1,287,698

 

 

 

1,597,752

 

 

 

 

19,400,357

 

 

 

17,588,407

 

 

16. Risk management activities

The Group’s risk management activities are the same as disclosed in Note 17 of the consolidated financial statements for the year ended December 31, 2024.

17. Fair values

Fair values of cash balances, trade receivables, trade payables, and other current liabilities approximate their carrying amounts largely due to the short-term maturities of these instruments.

 

The fair value of the cash equivalents, Group’s financial instruments measured at fair value on recurring basis, is categorized within level 1 of the fair value hierarchy, as the valuation is based on quoted net asset values (NAV) in active markets at the reporting date.

13


 

18. Share-based payments

In 2016, the Company implemented an Equity Incentive Plan (the “Plan”) in order to advance the interests of the Company’s shareholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to the Company and by providing such persons with performance-based incentives that are intended to better align the interests of such persons with those of the Company’s shareholders. This plan has been superseded by the 2021 Equity Incentive Plan (the “2021 Plan”).

Set out below is an overview of changes in the Stock Options and Restricted Stock Units (“RSUs”) during the six months ended June 30, 2025.

 

 

 

Stock Options

 

 

RSUs

 

 

 

Outstanding
options

 

 

Weighted
average
exercise
price

 

 

Outstanding
RSUs

 

 

 

 

 

 

 

 

 

 

Outstanding January 1, 2025

 

 

3,869,188

 

 

 

12.36

 

 

 

1,272,790

 

Granted

 

 

630,000

 

 

 

14.74

 

 

 

614,655

 

Exercised (Vested and Settled)

 

 

(138,635

)

 

 

1.66

 

 

 

(286,389

)

Forfeited

 

 

 

 

 

 

 

 

(18,219

)

Expired Options

 

 

(139,167

)

 

 

16.55

 

 

 

 

Outstanding June 30, 2025

 

 

4,221,386

 

 

 

12.29

 

 

 

1,582,837

 

 

During the six months ended June 30, 2025, a total of 403,655 RSUs were granted to employees that joined the Group in the same period and to existing employees. The RSUs shall vest equally over a four-year period on each of the four anniversaries of the vesting start date until either the RSUs are fully vested or the RSUs holders’ continuous service terminates.

During the six months ended June 30, 2025, 186,000 RSUs were issued to existing key management. The RSUs shall vest over a four-year period, with 25% of the aggregate number of RSUs vesting on the 12-month anniversary of the vesting commencement date, and thereafter 1/48th of the aggregate number of RSUs vesting on each subsequent monthly anniversary of the vesting commencement date, subject to continuous service through each applicable vesting date.

During the six months ended June 30, 2025, 25,000 RSUs were issued to members of the Board of Directors. The RSUs shall vest on the 12-month anniversary of the vesting start date.

The fair value of the RSUs is determined based on the share value per ordinary share at the grant date (or at the first trading day after the grant date if the Nasdaq Stock Exchange is not open on this date). The grant dates and share closing prices for grants during the first three months of 2025 were: February 1 (€16.57), March 1 (€14.60), March 12 (€14.71), April 1 (€13.74), and May 1 (€15.80), respectively.

On March 12, 2025, a total of 75,000 stock options were granted to members of the Board of Directors with an exercise price of €14.74 per share with a final exercise date of March 11, 2035, unless forfeited or exercised on an earlier date. 100% of the aggregate number of shares subject to the option shall vest on the 12-month anniversary of the vesting commencement date, subject to the option holder’s continuous service.

On March 12, 2025, a total of 555,000 stock options were granted to members of key management with an exercise price of €14.74 per share with a final exercise date of March 11, 2035, unless forfeited or exercised on an earlier date. 25% of the aggregate number of shares subject to the option shall vest on the 12-month anniversary of the vesting commencement date, and thereafter 1/48th of the aggregate number of shares subject to the option shall vest on each subsequent monthly anniversary of the vesting commencement date, subject to the option holder’s continuous service through each applicable vesting date.

As of June 30, 2025, a total number of 2,601,619 stock options are exercisable (June 30, 2024: 4,221,271).

For the six months ended June 30, 2025, the Group recognized 9.6 million of share-based payment expense in the unaudited condensed consolidated statement of income or loss and other comprehensive income (six months ended June 30, 2024: €6.3 million).

The inputs and outputs used in the measurement of the fair value per option at each grant/ measurement date using the Black-Scholes formula (including the related number of options and the fair value of the options) were as follows:

 

14


 

 

 

March 12, 2025

 

March 12, 2025

 

Number of options

 

 

75,000

 

 

555,000

 

Fair value of the options

 

11.86

 

12.19

 

Fair value of the ordinary shares

 

14.71

 

14.71

 

Exercise price

 

14.74

 

14.74

 

Expected volatility (%)

 

 

105

%

 

105

%

Expected life (years)

 

5.5

 

 

6.1

 

Risk-free interest rate (%)

 

 

4.3

%

 

4.3

%

Expected dividend yield

 

 

 

 

 

 

19. Basic and diluted loss per share

Basic and diluted loss per share is calculated by dividing the loss attributable to equity holders of the Company by the weighted average number of issued and outstanding ordinary shares during the three months ended June 30, 2025 and 2024.

All of the Company’s potential dilutive securities have been excluded from the computation of diluted net loss per share attributable to ordinary stockholders as the effect of including them would be antidilutive.

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

 

Net Loss

 

 

(45,480,686

)

 

 

(29,731,073

)

 

(91,821,509

)

 

(57,749,829

)

Weighted average number of ordinary shares outstanding

 

 

54,688,182

 

 

 

53,939,597

 

 

54,588,321

 

 

53,843,789

 

Basic and diluted loss per share

 

 

(0.83

)

 

 

(0.55

)

 

(1.68

)

 

(1.07

)

 

20. Commitments and Contingencies

Claims

There are no material claims known to management related to the activities of the Group.

Commitments

The Group's contractual obligations and commitments as of June 30, 2025 amounted to €133 million, (December 31, 2024: €109.9 million) primarily related to research and development activities.

The Group had no contingent liabilities and no contingent assets as of June 30, 2025 and December 31, 2024.

21. Related parties

Note 1.2 provides information about the Group’s structure, including details of the subsidiaries and the holding company. The following provides the total amount of transactions that have been entered into with related parties for the relevant financial period.

Key management personnel compensation

 

 

 

For the three months ended June 30,

 

For the six months ended June 30,

 

 

 

2025

 

2024

 

2025

 

2024

 

 

 

 

 

 

 

Short term employee benefits

 

 

1,208,362

 

 

1,300,557

 

 

2,617,978

 

 

2,661,986

 

Post employee benefits

 

 

62,837

 

 

62,130

 

 

133,012

 

 

126,189

 

Share-based payments

 

 

3,091,132

 

 

2,088,045

 

 

5,952,342

 

 

3,400,920

 

Total

 

 

4,362,331

 

 

3,450,732

 

 

8,703,332

 

 

6,189,095

 

 

The Group engages a management entity for the purpose of providing key management services and/or strategic advisory services to the Company. This management entity is considered a related party, as it provides key management advisory services and exercises key management functions.

 

15


 

The aggregate amount of expense recognized in the unaudited condensed consolidated interim financial statements related to this related party was €0.4 million in each of the six months ended June 30, 2025 and 2024, respectively.

 

The outstanding balances payable to key management personnel, or entities which they control, as per June 30, 2025 and December 31, 2024 were €0.8 million and €1.5 million, respectively.

 

16


 

22. Events after the reporting period

 

On July 22, 2025, the Company entered into an underwriting agreement with Morgan Stanley & Co. LLC and Leerink Partners LLC as representatives of the underwriters named therein, pursuant to which the Company agreed to issue and sell in an underwritten offering (i) 9,562,500 ordinary shares, par value €0.12 per share (which includes the exercise in full by the underwriters of their option to purchase up to an additional 1,312,500 ordinary shares) and (ii) pre-funded warrants to purchase up to 500,000 ordinary shares. The offering closed on July 24, 2025, and the Company generated net proceeds of approximately $189 million, after deducting bank fees of approximately $12 million.

 

 

 

 

17


 

Signatories to the unaudited condensed consolidated interim financial statements

Leiden, August 12, 2025

 

 

Pharvaris N.V.

Board of Directors

 

 

 

 

B.A.E. Modig

R.H. Glassman

 

 

 

 

E. Björk

J.G.C.P. Schikan

 

 

 

 

D.P. Meeker

V. Monges

 

 

 

 

 

 

 

 

 

18