Exhibit 107

Calculation of Filing Fee Table

S-3

(Form Type)

Gain Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered (1)

Proposed Maximum Offering Price Per Share (2)

Maximum Aggregate Offering Price (3)

Fee Rate

Amount of Registration Fee

Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Fees to Be Paid

Equity

Common stock, par value $0.0001 per share

457(o)

Equity

Preferred stock, par value $0.0001 per share

457(o)

Debt

Debt securities

457(o)

Other

Warrants

457(o)

Other

Subscription Rights

457(o)

Other

Units

457(o)

Unallocated (Universal) Shelf

(1)

457(o)

$

100,000,000.00

0.00015310

$

15,310.00

Total Offering Amounts

$

100,000,000.00

$

15,310.00

Total Fees Previously Paid

--

Total Fee Offsets

--

Net Fee Due

$

15,310.00

(1) The amount to be registered consists of up to $100,000,000 of an indeterminate amount of common stock, preferred stock, debt securities, warrants, subscription rights and/or units. There is also being registered hereunder such currently indeterminate number of (i) shares of common stock or other securities of the registrant as may be issued upon conversion of, or in exchange for, convertible or exchangeable debt securities and/or preferred stock registered hereby, or (ii) shares of preferred stock, common stock, debt securities, subscription rights or units as may be issued upon exercise of warrants registered hereby, as the case may be. Any securities registered hereunder may be sold separately or as units with the other securities registered hereunder. The securities registered hereunder also include an indeterminate number of securities as may be issued pursuant to anti-dilution provisions of any of such securities. In addition, pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this registration statement also covers any additional securities that may be offered or issued in connection with any stock splits, stock dividends or similar transactions.

(2) The proposed maximum aggregate offering price per share will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security pursuant to Instruction 2.A.ii.b. to Item 16(b) of Form S-3 under the Securities Act.

(3) Estimated solely for purposes of computing the registration fee. No separate consideration will be received for (i) common stock or other securities of the registrant that may be issued upon conversion of, or in exchange for, convertible or exchangeable debt securities and/or preferred stock registered hereby, or (ii) preferred stock, common stock, debt securities, subscription rights or units that may be issued upon exercise of warrants registered hereby, as the case may be.