S-3 S-3ASR EX-FILING FEES 0001783183 Phathom Pharmaceuticals, Inc. N/A N/A 0001783183 2026-01-05 2026-01-05 0001783183 1 2026-01-05 2026-01-05 0001783183 2 2026-01-05 2026-01-05 0001783183 3 2026-01-05 2026-01-05 0001783183 4 2026-01-05 2026-01-05 0001783183 5 2026-01-05 2026-01-05 0001783183 6 2026-01-05 2026-01-05 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

Phathom Pharmaceuticals, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Common Stock, $0.0001 par value per share 457(r) 0.0001381
Fees to be Paid 2 Equity Preferred Stock, $0.0001 par value per share 457(r) 0.0001381
Fees to be Paid 3 Debt Debt Securities 457(r) 0.0001381
Fees to be Paid 4 Other Warrants 457(r) 0.0001381
Fees to be Paid 5 Other Units 457(r) 0.0001381
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities 6 Equity Common Stock, $0.0001 par value per share 415(a)(6) 5,827,416 $ 228,434,707.20 S-3 333-275431 11/17/2023 $ 0.00

Total Offering Amounts:

$ 228,434,707.20

$ 0.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 0.00

Offering Note

1

(1) Omitted pursuant to Form S-3 General Instruction II.E. Includes rights to acquire common stock or preferred stock of the Phathom Pharmaceuticals, Inc. (the "Registrant") under any shareholder rights plan then in effect, if applicable under the terms of any such plan. (2) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices and, in addition, an unspecified number of additional shares of Common Stock is being registered as may be issued from time to time upon conversion of any Debt Securities that are convertible into Common Stock or pursuant to any anti-dilution adjustments with respect to any such convertible Debt Securities. (3) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the registrant is deferring payment of the entire registration fee.

2

(1) Omitted pursuant to Form S-3 General Instruction II.E. Includes rights to acquire common stock or preferred stock of the Phathom Pharmaceuticals, Inc. (the "Registrant") under any shareholder rights plan then in effect, if applicable under the terms of any such plan. (2) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices and, in addition, an unspecified number of additional shares of Common Stock is being registered as may be issued from time to time upon conversion of any Debt Securities that are convertible into Common Stock or pursuant to any anti-dilution adjustments with respect to any such convertible Debt Securities. (3) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the registrant is deferring payment of the entire registration fee.

3

(1) Omitted pursuant to Form S-3 General Instruction II.E. Includes rights to acquire common stock or preferred stock of the Phathom Pharmaceuticals, Inc. (the "Registrant") under any shareholder rights plan then in effect, if applicable under the terms of any such plan. (2) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices and, in addition, an unspecified number of additional shares of Common Stock is being registered as may be issued from time to time upon conversion of any Debt Securities that are convertible into Common Stock or pursuant to any anti-dilution adjustments with respect to any such convertible Debt Securities. (3) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the registrant is deferring payment of the entire registration fee.

4

(1) Omitted pursuant to Form S-3 General Instruction II.E. Includes rights to acquire common stock or preferred stock of the Phathom Pharmaceuticals, Inc. (the "Registrant") under any shareholder rights plan then in effect, if applicable under the terms of any such plan. (2) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices and, in addition, an unspecified number of additional shares of Common Stock is being registered as may be issued from time to time upon conversion of any Debt Securities that are convertible into Common Stock or pursuant to any anti-dilution adjustments with respect to any such convertible Debt Securities. (3) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the registrant is deferring payment of the entire registration fee.

5

(1) Omitted pursuant to Form S-3 General Instruction II.E. Includes rights to acquire common stock or preferred stock of the Phathom Pharmaceuticals, Inc. (the "Registrant") under any shareholder rights plan then in effect, if applicable under the terms of any such plan. (2) An unspecified number of securities or aggregate principal amount, as applicable, is being registered as may from time to time be offered at unspecified prices and, in addition, an unspecified number of additional shares of Common Stock is being registered as may be issued from time to time upon conversion of any Debt Securities that are convertible into Common Stock or pursuant to any anti-dilution adjustments with respect to any such convertible Debt Securities. (3) In accordance with Rules 456(b) and 457(r) under the Securities Act of 1933, as amended, the registrant is deferring payment of the entire registration fee.

6

The Registrant previously registered securities having an aggregate offering price of up to $500,000,000 pursuant to a Registration Statement on Form S-3 (Registration No. 333-275431) (the "Prior Registration Statement"), filed with the Securities and Exchange Commission on November 9, 2023 and declared effective on November 17, 2023. In connection with the filing of the Prior Registration Statement, the Registrant made a contemporaneous registration fee payment with respect to the accompanying resale prospectus (the "Prior Resale Prospectus") registering the resale of up to 5,827,416 shares held by the selling stockholder named therein, all of which remain unsold under the Prior Registration Statement as of the date of this registration statement. The Prior Resale Prospectus will be terminated as of the date of this Registration Statement on Form S-3. Pursuant to Rule 457(p), $24,922.25 of the registration fee previously paid in connection with the Prior Resale Prospectus under the Prior Registration Statement will be applied to the fees payable pursuant to this registration statement.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A