S-3 S-3ASR EX-FILING FEES 0001770121 Sana Biotechnology, Inc. N/A N/A 0001770121 2026-03-03 2026-03-03 0001770121 1 2026-03-03 2026-03-03 0001770121 2 2026-03-03 2026-03-03 0001770121 3 2026-03-03 2026-03-03 0001770121 4 2026-03-03 2026-03-03 0001770121 5 2026-03-03 2026-03-03 0001770121 6 2026-03-03 2026-03-03 0001770121 7 2026-03-03 2026-03-03 0001770121 8 2026-03-03 2026-03-03 0001770121 9 2026-03-03 2026-03-03 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

Sana Biotechnology, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Common Stock, $0.0001 par value per share 457(r) 0.0001381
Fees to be Paid 2 Equity Preferred Stock, $0.0001 par value per share 457(r) 0.0001381
Fees to be Paid 3 Debt Debt Securities 457(r) 0.0001381
Fees to be Paid 4 Equity Depositary Shares 457(r) 0.0001381
Fees to be Paid 5 Other Warrants 457(r) 0.0001381
Fees to be Paid 6 Other Subscription Rights 457(r) 0.0001381
Fees to be Paid 7 Other Purchase Contracts 457(r) 0.0001381
Fees to be Paid 8 Other Units 457(r) 0.0001381
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities 9 Other Unallocated (Universal) Shelf 415(a)(6) $ 216,385,563.00 S-3 333-277584 03/21/2025 $ 33,128.63

Total Offering Amounts:

$ 216,385,563.00

$ 0.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 0.00

Offering Note

1

(i) The securities registered hereunder include such indeterminate number of (a) shares of common stock, (b) shares of preferred stock, (c) debt securities, (d) depositary shares, (e) warrants to purchase common stock, preferred stock or other securities of the registrant, (f) subscription rights, (g) purchase contracts, and (h) units consisting of some or all of these securities in any combination, as may be sold from time to time by the registrant. There are also being registered hereunder an indeterminate number of shares of common stock and preferred stock as shall be issuable upon conversion, exchange or exercise of any securities that provide for such issuance. (ii) Pursuant to Rule 416 under the Securities Act of 1933, as amended, or the Securities Act, this registration statement shall also cover any additional shares of the registrant's securities that become issuable by reason of any stock splits, stock dividend or similar transaction. (iii) The proposed maximum per security and aggregate offering prices per class of securities will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security. Separate consideration may or may not be received for securities that are issuable on exercise, conversion or exchange of other securities, or that are issued in units. (iv) In accordance with Rules 456(b) and 457(r) under the Securities Act, the registrant is deferring payment of the entire registration fee other than the registration fee due in connection with $150,000,000 of shares of common stock that may be issued and sold from time to time under the at-the-market offering prospectus supplement included herein, all of which are Unsold Securities (as defined below) being carried forward (see footnote 9 below). Any subsequent registration fees will be paid on a pay-as-you-go basis.

2

See note 1.

3

See note 1.

4

See note 1.

5

See note 1.

6

See note 1.

7

See note 1.

8

See note 1.

9

Pursuant to 415(a)(6) under the Securities Act, the securities registered pursuant to this registration statement include unsold securities previously registered by the registrant on the registrant's shelf registration statement on Form S-3 (File No. 333-277584), originally filed on March 1, 2024, as amended on March 14, 2025 and March 17, 2025 (the "Prior Registration Statement"). The Prior Registration Statement registered the offer and sale of an indeterminate number of (a) shares of common stock, (b) shares of preferred stock, (c) debt securities, (d) depositary shares, (e) warrants to purchase common stock, preferred stock or other securities of the registrant, (f) subscription rights, (g) purchase contracts, and (h) units consisting of some or all of these securities in any combination up to an aggregate offering price of $350,000,000, including, pursuant to the prospectus supplement dated May 8, 2025, up to $119,000,000 in shares of the registrant's common stock (the "ATM Shares") that may be issued and sold under a certain sales agreement with TD Securities (USA) LLC. The registrant previously paid a fee of $53,585.00 related to such $350,000,000 in shares of common stock, of which $216,385,563 remain unsold (the "Unsold Securities), including $71,635,408 of the ATM Shares (the "Unsold ATM Securities"). The registrant has determined to include in this registration statement the Unsold Securities, including the Unsold ATM Securities, and no additional filing fee is due with respect to the Unsold Securities in connection with the filing of this registration statement.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A