Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Cyclerion Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

	Security Type	Security Class Title	Fee Calculation Rule	Amount  Registered(1)	Proposed Maximum Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of Registration Fee
Fees to Be Paid	Equity	Common Stock, no par value per share	457(c)	499,998	$3.26(2)	$1,629,993.48	0.00015310	$249.56
	Total Offering Amounts					$1,629,993.48		$249.56
	Total Fees Previously Paid							—
	Total Fee Offsets							—
	Net Fee Due							$249.56

(1) Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the shares of common stock offered hereby also include an indeterminate number of additional shares of common stock as may from time to time become issuable by reason of share splits, share dividends, recapitalizations or other similar transactions.

(2) Estimated at $3.26 per ordinary share, the average of the high and low prices as reported on The Nasdaq Capital Market on May 2, 2025, for the purpose of calculating the registration fee in accordance with Rule 457(c) under the Securities Act.