EX-99.1

Seer Reports Second Quarter 2025 Financial Results and Reiterates Full Year 2025 Outlook

Revenue grew 32% year-over-year, driven by increased product sales and service revenue

Launched new high-throughput Proteograph® ONE assay and SP200 automation instrument

REDWOOD CITY, Calif. August 6, 2025 – Seer, Inc. (Nasdaq: SEER), a leading life sciences company commercializing a disruptive new platform for proteomics, today reported financial results for the second quarter ended June 30, 2025.

Recent Highlights

•

Achieved revenue of $4.1 million for the second quarter of 2025

•

Launched new high-throughput Proteograph ONE assay and SP200 automation instrument, enabling previously unattainable scale and efficiency

•

Announced a collaboration with Korea University to launch a 20,000-sample population-scale proteomics study utilizing the Proteograph ONE assay to develop AI-driven diagnostics for cancers in young adults

•

Accelerated third-party validation through impactful data presentations and publications from key opinion leaders at recent conferences

•

Ended the quarter with approximately $263.3 million of cash, cash equivalents and investments

“Our team delivered a solid second quarter and achieved a pivotal milestone with the launches of our high-throughput Proteograph ONE assay and SP200 instrument, which significantly enhance the scalability and efficiency of our platform,” said Omid Farokhzad, Chair and CEO of Seer. “Seer was founded on the belief that we could transform the field of deep, unbiased proteomics. It’s incredibly rewarding to see that vision come to fruition, with our technology now powering multiple population-scale studies. I’m deeply proud of our team’s relentless focus on innovation and execution, even with continued macroeconomic pressures affecting our customer base.”

Second Quarter 2025 Financial Results

Revenue was $4.1 million for the second quarter of 2025, a 32% increase from $3.1 million for the corresponding prior year period, primarily due to higher product sales and service revenue in the quarter. Product revenue for the second quarter of 2025 was $2.7 million and consisted of sales of Proteograph instruments and consumable kits. Service revenue was $1.2 million for the second quarter of 2025, including $409 thousand of related party revenue, and primarily consisted of revenue related to Seer Technology Access Center service projects. Other revenue was $119 thousand for the second quarter of 2025.

Gross profit was $2.1 million and gross margin was 52% for the second quarter of 2025.

Operating expenses were $22.6 million for the second quarter of 2025, including $3.7 million of stock-based compensation, a decrease of 21% compared to $28.8 million for the corresponding prior year period, including $7.3 million of stock-based compensation. The decrease in operating expenses was primarily driven by a decrease in stock-based compensation.

Net loss was $19.4 million for the second quarter of 2025, compared to $22.9 million for the corresponding prior year period.

Cash, cash equivalents and investments were approximately $263.3 million as of June 30, 2025.

2025 Guidance

Seer continues to expect full year 2025 revenue to be in the range of $17 million to $18 million, representing growth of 24% at the midpoint over full year 2024.

Webcast Information

Seer will host a conference call to discuss the second quarter 2025 financial results on Wednesday, August 6, 2025 at 1:30 pm Pacific Time / 4:30 pm Eastern Time. A webcast of the conference call can be accessed at https://investor.seer.bio. The webcast will be archived and available for replay for at least 90 days after the event.

About Seer

Seer, Inc. (Nasdaq: SEER) sets the standard in deep, unbiased proteomics—delivering insights with a scale, speed, precision, and reproducibility previously unattainable. Seer’s Proteograph® Product Suite uniquely integrates proprietary engineered nanoparticles, streamlined automation instrumentation, optimized consumables, and advanced analytical software to solve challenges that conventional methods have failed to overcome. Traditional proteomic technologies have historically struggled with inconsistent data, limited throughput, and prohibitive complexity, but Seer’s robust and scalable workflow consistently reveals biological insights that others do not. Seer’s products are for research use only and are not intended for diagnostic procedures. For more information about Seer’s differentiated approach and ongoing leadership in proteomics, visit www.seer.bio.

Forward Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Such forward-looking statements are based on Seer’s beliefs and assumptions and on information currently available to it on the date of this press release. Forward-looking statements may involve known and unknown risks, uncertainties and other factors that may cause Seer’s actual results, performance, or achievements to be materially different from those expressed or implied by the forward-looking statements. These statements include but are not limited to statements regarding Seer’s expectations for future results of operations and its financial position, business strategy, partnerships, adoption of our products and outlook for fiscal year 2025. These and other risks are described more fully in Seer’s filings with the Securities and Exchange Commission (“SEC”) and other documents that Seer subsequently files with the SEC from time to time. Except to the extent required by law, Seer undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Investor Contact:

Carrie Mendivil

investor@seer.bio

Media Contact:

Patrick Schmidt

pr@seer.bio

SEER, INC.

Condensed Consolidated Statements of Operations and Comprehensive Loss

(Unaudited)

(in thousands, except share and per share amounts)


	Three Months Ended June 30,						Six Months Ended June 30,
	2025			2024			2025			2024
Revenue:
Product	$	2,726		$	1,761		$	5,616		$	3,429
Service		797			682			2,000			1,090
Related party		409			583			461			1,537
Other		119			46			179			82
Total revenue		4,051			3,072			8,256			6,138
Cost of revenue:
Product		1,167			701			2,541			1,692
Service		395			362			926			631
Related party		69			156			139			468
Other		309			122			478			255
Total cost of revenue		1,940			1,341			4,084			3,046
Gross profit		2,111			1,731			4,172			3,092
Operating expenses:
Research and development		11,985			12,734			23,335			24,999
Selling, general and administrative		10,656			16,093			22,098			30,381
Total operating expenses		22,641			28,827			45,433			55,380
Loss from operations		(20,530	)		(27,096	)		(41,261	)		(52,288	)
Other income (expense):
Interest income		2,992			4,433			6,209			9,019
Loss on equity method investment		(1,841	)		—			(3,416	)		—
Other income (expense)		3			(187	)		(755	)		(260	)
Total other income		1,154			4,246			2,038			8,759
Loss before provision for income taxes		(19,376	)		(22,850	)		(39,223	)		(43,529	)
Provision for income taxes		48			—			149			—
Net loss	$	(19,424	)	$	(22,850	)	$	(39,372	)	$	(43,529	)
Other comprehensive loss:
Unrealized gain (loss) on available-for-sale securities		2			(105	)		171			(434	)
Comprehensive loss	$	(19,422	)	$	(22,955	)	$	(39,201	)	$	(43,963	)
Net loss per share attributable to Class A and Class B common stockholders, basic and diluted	$	(0.33	)	$	(0.35	)	$	(0.67	)	$	(0.67	)
Weighted-average shares used in computing net loss per share attributable to Class A and Class B common stockholders, basic and diluted		58,087,565			64,576,399			58,744,490			64,581,228

SEER, INC.

Condensed Consolidated Balance Sheets

(Unaudited)

(in thousands, except share and per share amounts)


	June 30, 2025			December 31, 2024
ASSETS
Current assets:
Cash and cash equivalents	$	37,931		$	40,753
Short-term investments		171,895			195,657
Accounts receivable, net		3,905			3,997
Related party receivables		409			379
Other receivables		1,400			1,853
Inventory		7,512			7,436
Prepaid expenses and other current assets		2,586			3,248
Total current assets		225,638			253,323
Long-term investments		53,426			63,103
Operating lease right-of-use assets		21,657			22,791
Property and equipment, net		16,496			18,575
Restricted cash		524			524
Other assets		4,746			8,281
Total assets	$	322,487		$	366,597
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable	$	2,672		$	4,621
Accrued expenses		6,106			7,937
Deferred revenue		540			408
Operating lease liabilities, current		2,441			2,312
Other current liabilities		26			50
Total current liabilities		11,785			15,328
Operating lease liabilities, net of current portion		22,390			23,652
Other noncurrent liabilities		20			48
Total liabilities		34,195			39,028
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.00001 par value; 5,000,000 shares authorized as of June 30, 2025 and December 31, 2024; zero shares issued and outstanding as of June 30, 2025 and December 31, 2024		—			—
Class A common stock, $0.00001 par value; 94,000,000 shares authorized as of June 30, 2025 and December 31, 2024; 52,283,570 and 55,083,123 shares issued and outstanding as of June 30, 2025 and December 31, 2024, respectively		1			1
Class B common stock, $0.00001 par value; 6,000,000 shares authorized as of June 30, 2025 and December 31, 2024; 4,044,969 shares issued and outstanding as of June 30, 2025 and December 31, 2024		—			—
Additional paid-in capital		719,728			719,804
Accumulated other comprehensive gain		307			136
Accumulated deficit		(431,744	)		(392,372	)
Total stockholders’ equity		288,292			327,569
Total liabilities and stockholders’ equity	$	322,487		$	366,597