Calculation of Filing Fee Tables

S-8

INCYTE CORP

Table 1: Newly Registered Securities

	Security Type	Security Class Title	Fee Calculation Rule	Amount Registered	Proposed Maximum Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of Registration Fee
1	Equity	Common Stock, $.001 par value per share,	Other	1,000,000	$ 68.24	$ 68,240,000.00	0.0001531	$ 10,447.54
Total Offering Amounts:						$ 68,240,000.00		$ 10,447.54
Total Fee Offsets:								$ 0.00
Net Fee Due:								$ 10,447.54

Offering Note

¹ (1) Pursuant to Rule 416 under the Securities Act of 1933 (the "Securities Act"), the registration statement to which this exhibit relates also covers any additional shares of the Registrant's Common Stock, $.001 par value per share (the "Common Stock"), that may be offered or become issuable under the 2024 Inducement Stock Incentive Plan in connection with any stock split, stock dividend, recapitalization or any other similar transaction effected without receipt of consideration that results in an increase in the number of outstanding shares of the Common Stock. (2) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h)(1) under the Securities Act, based upon the average of the high and low sales prices of the Common Stock on The Nasdaq Stock Market on June 30, 2025. (3) The Registrant is not relying on Rule 457(p) under the Securities Act to offset any of the filing fee due with respect to the Registration Statement to which this exhibit relates and, accordingly, Table 2 has been omitted.