EDGAR Filing Documents for 0000874015-16-000112

Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]:

SEC Accession No. 0000874015-16-000112

Filing Date

2016-02-26

Accepted

2016-02-25 19:08:02

Documents

114

Period of Report

2015-12-31

Document Format Files

Seq	Description	Document	Type	Size
1	ISIS PHARMACEUTICALS INC 10-K 12-31-2015	form10k.htm	10-K	2612450
2	EXHIBIT 10.64	ex10_64.htm	EX-10.64	18393
3	EXHIBIT 21.1	exhibit21_1.htm	EX-21.1	2130
4	EXHIBIT 23.1	exhibit23_1.htm	EX-23.1	4957
5	EXHIBIT 31.1	exhibit31_1.htm	EX-31.1	12435
6	EXHIBIT 31.2	exhibit31_2.htm	EX-31.2	12428
7	EXHIBIT 32.1	exhibit32_1.htm	EX-32	6977
14		image00002.jpg	GRAPHIC	112488
15		image00004.jpg	GRAPHIC	714
16		image10.jpg	GRAPHIC	46106
17		image11.jpg	GRAPHIC	17854
18		image12.jpg	GRAPHIC	31669
19		image13.jpg	GRAPHIC	25608
20		image14.jpg	GRAPHIC	24762
21		image00015.jpg	GRAPHIC	33692
22		image00016.jpg	GRAPHIC	129581
23		image00017.jpg	GRAPHIC	46168
24		image00018.jpg	GRAPHIC	72437
25		image00019.jpg	GRAPHIC	33252
26		image00020.jpg	GRAPHIC	66324
27		image00021.jpg	GRAPHIC	18221
28		image00022.jpg	GRAPHIC	28664
29		image00023.jpg	GRAPHIC	20225
30		image00024.jpg	GRAPHIC	37223
31		image00025.jpg	GRAPHIC	68776
	Complete submission text file	0000874015-16-000112.txt		14971067

Data Files

Seq	Description	Document	Type	Size
8	XBRL INSTANCE DOCUMENT	ions-20151231.xml	EX-101.INS	2758958
9	XBRL TAXONOMY EXTENSION SCHEMA	ions-20151231.xsd	EX-101.SCH	103013
10	XBRL TAXONOMY EXTENSION CALCULATION LINKBASE	ions-20151231_cal.xml	EX-101.CAL	114068
11	XBRL TAXONOMY EXTENSION DEFINITION LINKBASE	ions-20151231_def.xml	EX-101.DEF	866251
12	XBRL TAXONOMY EXTENSION LABEL LINKBASE	ions-20151231_lab.xml	EX-101.LAB	1412487
13	XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE	ions-20151231_pre.xml	EX-101.PRE	1027859

Mailing Address 2855 GAZELLE COURT CARLSBAD CA 92010

Business Address 2855 GAZELLE COURT CARLSBAD CA 92010 7609319200

IONIS PHARMACEUTICALS INC (Filer) CIK: 0000874015 (see all company filings)