EXHIBIT 23

Consent of Independent Registered Public Accounting Firm

To the Board of Directors

Pfizer Inc.:

We consent to the incorporation by reference in the registration statements listed below of Pfizer Inc. and Subsidiary Companies (Pfizer Inc.) of our reports dated February 24, 2022, with respect to the consolidated balance sheets of Pfizer Inc. as of December 31, 2021 and 2020, the related consolidated statements of income, comprehensive income, equity, and cash flows for each of the years in the three-year period ended December 31, 2021, and the related notes, and the effectiveness of internal control over financial reporting as of December 31, 2021, which reports appear in the 2021 Annual Report on Form 10-K of Pfizer Inc.

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/s/ KPMG LLP

New York, New York February 24, 2022