Filed Pursuant to Rule 433

Registration No. 333-263304

Dated: August 4, 2022

Pricing Term Sheet

This term sheet provides information concerning a reopening (as discussed below) of JPMorgan Chase & Co.’s Fixed-to-Floating Rate Notes due 2033 described under “Description of the Notes” in the Prospectus Supplement dated April 19, 2022 to the Prospectus dated April 11, 2022 (the “Prospectus Supplement”) and, with respect to this reopening, supplements the information included in the Prospectus Supplement.

Issuer: JPMorgan Chase & Co.

Security Type: SEC Registered Senior Notes

Security: Fixed-to-Floating Rate Notes due 2033

Currency: USD

Reopening Size: $500,000,000

Total Amount Outstanding Following Reopening: $2,500,000,000

Maturity: April 26, 2033

Fixed Rate Period: From and including April 26, 2022 to but excluding April 26, 2032

Floating Rate Period: From and including April 26, 2032 to but excluding Maturity

Payment Frequency: Semi-annual during the Fixed Rate Period and quarterly during the Floating Rate Period

Day Count Fraction: 30/360 during the Fixed Rate Period, Actual/360 during the Floating Rate Period

Benchmark Treasury: 2.875% due May 15, 2032

Benchmark Treasury Yield: 2.672%

Spread to Benchmark Treasury: +172 basis points

Reoffer Yield: 4.392%

Fixed Rate Coupon: 4.586%, payable semiannually in arrears during the Fixed Rate Period.

Floating Rate Coupon: An annual floating rate equal to the Floating Rate Index plus a spread of 1.80% per annum, payable quarterly in arrears during the Floating Rate Period.

Floating Rate Index: Benchmark rate (expected to be Compounded SOFR as described under “Description of the Notes—Interest on the notes” in the Prospectus Supplement.)

Floating Rate Reset Frequency: Quarterly during the Floating Rate Period

Price to Public: 101.514% of face amount plus accrued and unpaid interest of $6,687,916.67 from, and including, April 26, 2022 to, but excluding, August 11, 2022.

Proceeds (Before Expenses) to Issuer: $505,320,000.00 (101.064%) plus accrued and unpaid interest of $6,687,916.67 from, and including, April 26, 2022 to, but excluding, August 11, 2022.

Interest Payment Dates: During the Fixed Rate Period, each April 26 and October 26, beginning October 26, 2022 and including April 26, 2032, and during the Floating Rate Period, each of July 26, 2032, October 26, 2032, January 26, 2033 and April 26, 2033.

Business Day: New York

Business Day Convention: During the Fixed Rate Period, following business day. During the Floating Rate Period, modified following business day.

Optional Redemption: We may redeem the notes, at our option, in whole at any time or in part from time to time, on or after October 26, 2022 and prior to April 26, 2032 upon at least 5 days’ but no more than 60 days’ notice to holders of the notes, at a redemption price equal to the greater of: (i) (a) the sum of the present values of the remaining scheduled payments

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of principal and interest on the notes to be redeemed discounted to the redemption date (assuming the notes matured on April 26, 2032) on a semi-annual basis (assuming a 360-day year consisting of twelve 30- day months) at the “Treasury Rate” plus 25 basis points less (b) interest accrued on those notes to the date of redemption; and (ii) 100% of the principal amount of the notes being redeemed; plus, in either case, accrued and unpaid interest on the notes to be redeemed to the redemption date.

In addition, we may redeem the notes, at our option, in whole, but not in part, on April 26, 2032 upon at least 5 days’ but no more than 60 days’ notice to holders of the notes, at a redemption price equal to 100% of the principal amount of the notes being redeemed plus accrued and unpaid interest thereon to the redemption date.

In addition, we may redeem the notes, at our option, in whole at any time or in part from time to time, on or after January 26, 2033, upon at least 5 days’ but no more than 60 days’ notice to holders of the notes, at a redemption price equal to 100% of the principal amount of the notes being redeemed plus accrued and unpaid interest thereon to the redemption date.

The foregoing supplements and supersedes the information set forth under “Description of the Notes” in the Prospectus Supplement.

CUSIP/ISIN: 46647PDC7 / US46647PDC77

Trade Date: August 4, 2022

Settlement Date: August 11, 2022 (T+5)

Denominations: $2,000 x $1,000

Sole Bookrunner: J.P. Morgan Securities LLC

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Co-Managers: CastleOak Securities, L.P.

Tigress Financial Partners, LLC

The notes are being offered as part of a reopening of a series of previously issued notes, as described in the prospectus supplement relating to this offering. The notes offered hereby will have the same terms (except as to issue date and issue price) as, and will be fungible with, the notes previously issued.

Settlement Period: The closing will occur on August 11, 2022 which will be more than two U.S. business days after the date of this pricing term sheet. Rule 15c6-1 under the Securities Exchange Act of 1934 generally requires that securities trades in the secondary market settle in two business days, unless the parties to a trade expressly agree otherwise.

JPMorgan Chase & Co. has filed a registration statement (including a prospectus, as supplemented by a prospectus supplement) with the Securities and Exchange Commission, or SEC, for the offering to which this term sheet relates. Before you invest, you should read the prospectus in that registration statement, the prospectus supplement and any other documents relating to this offering that JPMorgan Chase & Co. has filed with the SEC for more complete information about JPMorgan Chase & Co. and this offering. You may get these documents without cost by visiting EDGAR on the SEC Web site at www.sec.gov. Alternatively, the issuer, any underwriter or any dealer participating in the offering will arrange to send you the prospectus if you request it by calling collect 1-212-834-4533.

Any disclaimer or other notice that may appear below is not applicable to this communication and should be disregarded. Such disclaimer or notice was automatically generated as a result of this communication being sent by Bloomberg or another email system.

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