From: Pamela Murphy
Sent: November 27, 2006
To: rule-comments@sec.gov
Subject: SR-NASDAQ-2006-040

NASDAQ wants to increase our rates so we "can" use their recently acquired newswire service

I'd prefer they offer us this service at a compelling rate and let us decide if the offer is in our shareholders best interest.

To be held captive by NASDAQ and have them basically force us to use their services is "nuts" -- just because they want to grow their business shouldn't mean we have to pay for their growth. They should compete on competencies just as all of us do.

Sincerely,

Pam

Pamela Murphy
VP Investor Relations & Corporate Communications
Incyte Corporation
302/498-6944