-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 QWWdpnjUbfuesRj5BC7/ZwfA095gzTV50xzi/bEK5K7IWFN9BiXXD1TW/x2Pd0x0
 RkoncnuETsTtTLYcl/2W1g==

<SEC-DOCUMENT>0001181431-10-025472.txt : 20100510
<SEC-HEADER>0001181431-10-025472.hdr.sgml : 20100510
<ACCEPTANCE-DATETIME>20100510162901
ACCESSION NUMBER:		0001181431-10-025472
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100507
FILED AS OF DATE:		20100510
DATE AS OF CHANGE:		20100510

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NUTRI SYSTEM INC /DE/
		CENTRAL INDEX KEY:			0001096376
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-CATALOG & MAIL-ORDER HOUSES [5961]
		IRS NUMBER:				233012204
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		300 WELSH ROAD
		STREET 2:		BUILDING 1, SUITE 100
		CITY:			HORSHAM
		STATE:			PA
		ZIP:			19044
		BUSINESS PHONE:		2157065332

	MAIL ADDRESS:	
		STREET 1:		300 WELSH ROAD
		STREET 2:		BUILDING 1, SUITE 100
		CITY:			HORSHAM
		STATE:			PA
		ZIP:			19044

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MUSSER WARREN V
		CENTRAL INDEX KEY:			0000935363

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28551
		FILM NUMBER:		10816647

	MAIL ADDRESS:	
		STREET 1:		800 THE SAFEGUARD BUILDING
		STREET 2:		435 DEVON PARK DRIVE
		CITY:			WAYNE
		STATE:			PA
		ZIP:			19087
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd274932.xml
<DESCRIPTION>SALE OF COMMON STOCK BY WARREN MUSSER
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-05-07</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001096376</issuerCik>
        <issuerName>NUTRI SYSTEM INC /DE/</issuerName>
        <issuerTradingSymbol>NTRI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000935363</rptOwnerCik>
            <rptOwnerName>MUSSER WARREN V</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>435 DEVON PARK DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 500</rptOwnerStreet2>
            <rptOwnerCity>WAYNE</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19087</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Shares, .001</value>
            </securityTitle>
            <transactionDate>
                <value>2010-05-07</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>22.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2267</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ David D. Clark</signatureName>
        <signatureDate>2010-05-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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